Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

Rationale The reconceptualization of substance use disorders (SUD) as a chronic
phenomenon calls for a paradigm shift in service provision, particularly by way of long-term …

Background The aim was to assess the relationships between social and material
deprivation and the use of tobacco, excessive alcohol and psychotropic drugs by both sexes …

Improving sleep quality is key to increasing life quality for the elderly. Clarifying the nature of
sleep conditions and the factors that influence such is necessary to enrich the base of …

BACKGROUND: The overall suicide rate in the US increased by 6% between 1981 and
1986 and declined by 18% between 1986 and 1999. Detailed descriptions of recent trends …

Older people living with HIV (OPLWH) have higher rates of substance use (tobacco, alcohol,
and other drugs) than their HIV-negative peers. Addressing health care needs of OPLWH …

Alcohol consumption in the older adult is of major concern with the advent of baby boomers
coming into the over 65-age bracket. Alcohol consumption has been touted as beneficial for …

Cell senescence is a cellular process in which normal diploid cells cease to replicate and is
a major driving force for human cancers and aging-associated diseases. Recent studies on …

The use of vaccines against infectious microbes has been critical to the advancement of
medicine. Vaccine strategies combined with, or without, adjuvants have been established to …

Background Older individuals are consuming alcohol more frequently yet there is limited
evidence on the effectiveness of current interventions. This systematic review aims to …