[HTML][HTML] Pathophysiology of the antiphospholipid syndrome
PG De Groot, R Derksen - Journal of Thrombosis and Haemostasis, 2005 - Elsevier
Antiphospholipid syndrome is a distinct disorder with the clinical features of recurrent
thrombosis in the venous or arterial circulation and fetal losses. Its serological marker is the …
thrombosis in the venous or arterial circulation and fetal losses. Its serological marker is the …
Pregnancy loss and thrombophilia: the elusive link
Recurrent pregnancy loss (RPL) affects 1% pregnancies and is multi‐factorial in origin. The
role of the acquired thrombophilia antiphospholipid syndrome (APS) as a common and …
role of the acquired thrombophilia antiphospholipid syndrome (APS) as a common and …
Defective B cell tolerance checkpoints in systemic lupus erythematosus
S Yurasov, H Wardemann, J Hammersen… - The Journal of …, 2005 - rupress.org
A cardinal feature of systemic lupus erythematosus (SLE) is the development of
autoantibodies. The first autoantibodies described in patients with SLE were those specific …
autoantibodies. The first autoantibodies described in patients with SLE were those specific …
[HTML][HTML] Observational study of pregnant women with a previous spontaneous abortion before the 10th gestation week with and without antiphospholipid antibodies
C Chauleur, JP GALANAUD, S Alonso… - Journal of Thrombosis …, 2010 - Elsevier
Background: A clinical subtype of purely obstetrical antiphospholipid antibody (aPL‐Ab)
syndrome (APS) requires three or more unexplained consecutive embryonic losses before …
syndrome (APS) requires three or more unexplained consecutive embryonic losses before …
B cells in primary antiphospholipid syndrome: Review and remaining challenges
Y Dieudonné, A Guffroy, V Poindron, PS Sprauel… - Autoimmunity …, 2021 - Elsevier
It is now widely accepted that antiphospholipid antibodies (aPL) have direct pathogenic
effects and that B cells, notably through aPL production, play a key role in the development …
effects and that B cells, notably through aPL production, play a key role in the development …
Antiphospholipid antibodies overlapping in isolated neurological syndrome and multiple sclerosis: neurobiological insights and diagnostic challenges
C D'Angelo, O Franch, L Fernández-Paredes… - Frontiers in Cellular …, 2019 - frontiersin.org
Antiphospholipid syndrome (APS) is characterized by arterial and venous thrombosis,
pregnancy morbidity and fetal loss caused by pathogenic autoantibodies directed against …
pregnancy morbidity and fetal loss caused by pathogenic autoantibodies directed against …
Antiphospholipid antibodies: their origin and development
KJ Lackner, N Müller-Calleja - Antibodies, 2016 - mdpi.com
Antiphospholipid antibodies (aPL) are a hallmark of the antiphospholipid syndrome (APS),
which is the most commonly acquired thrombophilia. To date there is consensus that aPL …
which is the most commonly acquired thrombophilia. To date there is consensus that aPL …
The pathogenesis of obstetric APS: a 2023 update
C Mineo, PW Shaul, BL Bermas - Clinical Immunology, 2023 - Elsevier
The antiphospholipid syndrome (APS) is an autoimmune disease characterized by the
persistent presence of antibodies directed against phospholipids and phospholipid-binding …
persistent presence of antibodies directed against phospholipids and phospholipid-binding …
Lepidopteran cells, an alternative for the production of recombinant antibodies?
M Cérutti, J Golay - MAbs, 2012 - Taylor & Francis
Monoclonal antibodies are used with great success in many different therapeutic domains.
In order to satisfy the growing demand and to lower the production cost of these molecules …
In order to satisfy the growing demand and to lower the production cost of these molecules …
Antiphospholipid syndrome: looking for a refocusing
JC Gris, S Bouvier - Thrombosis Research, 2013 - Elsevier
The antiphospholipid syndrome (APS) is characterised by thrombotic or obstetric symptoms
associated with persistent antiphospholipid antibodies (aPL). Despite an increasing …
associated with persistent antiphospholipid antibodies (aPL). Despite an increasing …