Drug resistance is estimated to affect about a third of individuals with epilepsy, but its
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …

Abstract The International League Against Epilepsy (ILAE) Task Force on Nosology and
Definitions proposes a classification and definition of epilepsy syndromes in the neonate …

Objective This study was undertaken to gain consensus from experienced physicians and
caregivers regarding optimal diagnosis and management of Dravet syndrome (DS), in the …

Many epilepsy-associated genes have been identified over the last three decades, revealing
a remarkable molecular heterogeneity with the shared outcome of recurrent seizures …

Background and Objectives The genetic developmental and epileptic encephalopathies
(DEEs) comprise a large group of severe epilepsy syndromes, with a wide phenotypic …

Electroencephalography (EEG) serves as a diagnostic technique for measuring brain waves
and brain activity. Despite its precision in capturing brain electrical activity, certain factors …

Background and Objectives We aimed to determine the population-based cumulative
incidence and prevalence of developmental and epileptic encephalopathies (DEEs) and …

Objective The aim was to describe age at diagnosis, cumulative incidence, SCN1A variants,
mortality, seizure types and treatments in children with Dravet Syndrome (DS) in Sweden …

Missense variants in genes encoding ion channels are associated with a spectrum of severe
diseases. Variant effects on biophysical function correlate with clinical features and can be …

Dravet syndrome is a severe infantile onset developmental and epileptic encephalopathy
associated with mutations in the sodium channel alpha 1 subunit gene SCN1A. Prospective …