Background/Aim: Cancer research has been conducted using cultured cells as part of drug
discovery testing, but conventional two-dimensional culture methods are unable to reflect …

EGFR and some of the cognate ligands extensively traffic in extracellular vesicles (EVs) from
different biogenesis pathways. EGFR belongs to a family of four homologous tyrosine kinase …

Extracellular vesicles (EVs, including exosomes) are a group of heterogeneous nanometer‐
sized vesicles that are released by all types of cells and serve as functional mediators of cell …

Skin is the largest human organ and is continuously exposed to various exogenous and
endogenous trigger factors affecting body homeostasis. A number of mechanisms, including …

Abstract Background Desmoglein2 (DSG2) is a transmembrane protein that helps regulate
intercellular connections and contributes to desmosome assembly. Desmosome are …

Glioma is the most common form of primary central nervous malignant tumors. Vasculogenic
mimicry (VM) is a blood supply channel that is different from endothelial blood vessels in …

Gallbladder carcinoma (GBC) exhibits poor prognosis due to local recurrence, metastasis,
and resistance to targeted therapies. Using clinicopathological analyses of GBC patients …

ABSTRACT Human adenovirus type 55 (HAdV55) represents an emerging respiratory
pathogen and causes severe pneumonia with high fatality in humans. The cellular receptors …

Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis that is closely
associated with several human malignant diseases, while type I interferon (IFN-I) plays an …

Oral squamous cell carcinoma (OSCC) is the most prevalent malignancy in head and neck
cancer, with high recurrence and mortality. Early diagnosis and efficient therapeutic …