Bluetongue virus serotype 8 virus-like particles protect sheep against virulent virus infection as a single or multi-serotype cocktail immunogen

M Stewart, E Dubois, C Sailleau, E Bréard, C Viarouge… - Vaccine, 2013 - Elsevier
Since 1998, there have been multiple separate outbreaks of Bluetongue disease (BT) in
Europe with the largest outbreak ever recorded in Northern Europe caused by Bluetongue …

Safety and immunogenicity of three tetravalent dengue vaccine formulations in healthy adults in the USA

GH Dayan, M Thakur, M Boaz, C Johnson - Vaccine, 2013 - Elsevier
Background A candidate recombinant, live-attenuated, CYD tetravalent dengue vaccine
(CYD-TDV) has recently demonstrated immunogenicity, efficacy and good tolerability. This …

Nanoparticle-and Microparticle-Based Vaccines against Orbiviruses of Veterinary Importance

L Jiménez-Cabello, S Utrilla-Trigo, N Barreiro-Piñeiro… - Vaccines, 2022 - mdpi.com
Bluetongue virus (BTV) and African horse sickness virus (AHSV) are widespread
arboviruses that cause important economic losses in the livestock and equine industries …

Chimeric GII. 4 norovirus virus-like-particle-based vaccines induce broadly blocking immune responses

K Debbink, LC Lindesmith, EF Donaldson… - Journal of …, 2014 - Am Soc Microbiol
There is currently no licensed vaccine for noroviruses, and development is hindered, in part,
by an incomplete understanding of the host adaptive immune response to these highly …

[HTML][HTML] Call to action for dengue vaccine failure

S Mahalingam, BL Herring… - Emerging Infectious …, 2013 - ncbi.nlm.nih.gov
To the Editor: Dengue is one of the most widespread infectious diseases globally;
transmission now occurs in 128 countries. Although dengue virus (DENV) control strategies …

[HTML][HTML] Tree shrew as a new animal model for the study of dengue virus

L Jiang, C Lu, Q Sun - Frontiers in Immunology, 2021 - frontiersin.org
Dengue virus is a significant public health threat worldwide; however, the pathogenesis of
dengue disease remains poorly understood due to lack of appropriate small animal models …

Replication and excretion of the live attenuated tetravalent dengue vaccine CYD-TDV in a flavivirus-naive adult population: assessment of vaccine viremia and virus …

J Torresi, PC Richmond, LG Heron… - The Journal of …, 2017 - academic.oup.com
Background We assessed replication and excretion of the live attenuated tetravalent dengue
vaccine (CYD-TDV) into biological fluids following vaccination in dengue-naive adults in …

Interference and facilitation between dengue serotypes in a tetravalent live dengue virus vaccine candidate

KB Anderson, RV Gibbons, R Edelman… - Journal of Infectious …, 2011 - academic.oup.com
Background. Live, multivalent vaccines have historically exhibited interference in humans;
live dengue virus (DENV) vaccines have proven no exception. Methods. To characterize …

[HTML][HTML] Induction of neutralization antibodies in mice by Dengue-2 envelope DNA vaccines

ME PéREz-VélEz, T García-Nieves… - Puerto Rico health …, 2009 - ncbi.nlm.nih.gov
Background Dengue (DEN) viruses have become a public health problem that affects
approximately 100 million people worldwide each year. Prevention measures rely on vector …

A novel tetravalent formulation combining the four aggregated domain III-capsid proteins from dengue viruses induces a functional immune response in mice and …

E Suzarte, L Gil, I Valdés, E Marcos… - International …, 2015 - academic.oup.com
Our group developed a subunit vaccine candidate against dengue virus based on two
different viral regions: the domain III of the envelope protein and the capsid protein. The …