Among various gene therapy methods for cancer, suicide gene therapy attracts a special
attention because it allows selective conversion of non-toxic compounds into cytotoxic drugs …

The poor prognosis for patients with aggressive or metastatic tumors and the toxic side
effects of currently available treatments necessitate the development of more effective tumor …

Background Besides the use of temozolomide and radiotherapy for patients with favourable
methylation status, little progress has been made in the treatment of adult glioblastoma …

Being able to self-renew and differentiate into virtually all cell types, both human embryonic
stem cells (hESCs) and induced pluripotent stem cells (iPSCs) have exciting therapeutic …

Tumorigenesis is an important problem that needs to be addressed in the field of human
stem/progenitor cell transplantation for the treatment of subacute spinal cord injury (SCI) …

Gene therapy is defined as the treatment of disease by transfer of genetic material into cells.
This review will explore methods available for gene transfer as well as current and potential …

The treatment of cancer with common anti-proliferative agents generally suffers from an
insufficient differentiation between normal and malignant cells which results in extensive …

Over the last two decades gene therapy has moved from preclinical to clinical studies for
many diseases ranging from single gene disorders such as cystic fibrosis and Duchenne …

Current conventional treatments for cancer lack tumour selectivity resulting in the destruction
of healthy tissue and severe adverse effects to the patient in addition to limiting the …

The main drawback of most cancer chemotherapy is its relatively low ability to target tumour
cells versus normal cells. As a consequence, chemotherapy is usually connected with …