[HTML][HTML] The cardiac lipidome in models of cardiovascular disease

MM Tomczyk, VW Dolinsky - Metabolites, 2020 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death worldwide. There are
numerous factors involved in the development of CVD. Among these, lipids have an …

The lipid paradox in neuroprogressive disorders: causes and consequences

G Morris, M Berk, K Walder, A O'Neil, M Maes… - Neuroscience & …, 2021 - Elsevier
Chronic systemic inflammation is associated with an increased risk of cardiovascular
disease in an environment of low low-density lipoprotein (LDL) and low total cholesterol and …

[HTML][HTML] IL-10 attenuates OxPCs-mediated lipid metabolic responses in ischemia reperfusion injury

AK Bagchi, A Surendran, A Malik, DS Jassal… - Scientific reports, 2020 - nature.com
Oxidized phospholipids (OxPLs) promote inflammation as well as low density lipoprotein
(LDL) uptake in a variety of physiological and pathological states. Given the anti …

[HTML][HTML] Non-mitogenic FGF2 protects cardiomyocytes from acute doxorubicin-induced toxicity independently of the protein kinase CK2/heme oxygenase-1 pathway

N Koleini, BE Nickel, AL Edel, RR Fandrich… - Cell and Tissue …, 2018 - Springer
Abstract Doxorubicin (Dox)-induced cardiotoxicity, a limiting factor in the use of Dox to treat
cancer, can be mitigated by the mitogenic factor FGF2 in vitro, via a heme oxygenase 1 (HO …

Phospholipid and phospholipidomics in health and diseases

T Cai, F Yang - Lipidomics in health & disease: methods & application, 2018 - Springer
Phospholipids (PLs), which are of diverse chemical structures, are not only the major
component of the plasma membranes, but also act as signaling mediators for various …

Hydrophilic interaction liquid chromatography–electrospray ionization-tandem mass spectrometry of a complex mixture of native and oxidized phospholipids

I Losito, L Facchini, S Diomede, E Conte… - … of Chromatography A, 2015 - Elsevier
A mixture of native and oxidized phospholipids (PLs), generated by the soybean
lipoxygenase type V-catalyzed partial oxidation of a lipid extract obtained from human …

IL-10: A key molecule in the mitigation of heart failure

AK Bagchi, A Malik, G Akolkar, A Belló-Klein… - … Research: From Disease …, 2022 - Springer
Inflammatory mediators play an important role in the pathogenesis of several diseases
including heart failure. An appropriate balance between pro-inflammatory and anti …

Role of phospholipases and oxidized phospholipids in inflammation

D Hasanally, R Chaudhary, A Ravandi - Phospholipases in health and …, 2014 - Springer
Long thought of as a bystander in pathophysiological processes, lipid molecules have
emerged as bioactive mediators of cellular activity. Oxidized phospholipids (OxPLs) …

Investigating the role of SIRT3 in doxorubicin induced dilated cardiomyopathy

M Tomczyk - 2023 - mspace.lib.umanitoba.ca
Doxorubicin (DOX) is an effective anthracycline anti-neoplastic agent used for the treatment
of hematological and solid tumors. Advancements in cancer treatment over several decades …

Effects of sub-chronic dietary 2-monochloro-1, 3-propanediol on oxidized lipids in rat heart, kidney, serum, and skeletal muscle

L Cayer - 2019 - mspace.lib.umanitoba.ca
Chlorinated propanols are processing induced food contaminants formed in the
manufacturing of vegetable oils and hydrolyzed vegetable protein. The 2-monochloro …