Aging can cause attenuation in the functioning of multiple organs, and blood-brain barrier
(BBB) breakdown could promote the occurrence of disorders of the central nervous system …

Age-related cerebrovascular pathologies, ranging from cerebromicrovascular functional and
structural alterations to large vessel atherosclerosis, promote the genesis of vascular …

Context Vascular dysfunction is considered a hallmark of ageing that has been associated
with altered vasomotor responses, in which nitric oxide (NO) and reactive oxygen species …

Rapamycin (RAPA) is found to have neuro-protective properties in various
neuroinflammatory pathologies, including brain aging. With magnetic resonance imaging …

Background Alzheimer's disease (AD) is a neurodegenerative disorder and the predominant
type of dementia worldwide. It is characterized by the progressive and irreversible decline of …

Aims This study aims to investigate the mechanisms by which apolipoprotein E (APOE)
genotype modulates the relationship between low‐density lipoprotein receptor‐related …

Background and purpose Cognitive impairment is a prevalent adverse consequence of
traumatic brain injury (TBI). The neuroprotective effects of nicorandil (N‐(2‐hydroxyethyl) …

The microvascular inflow tract (MIT), comprising the penetrating arterioles, precapillary
sphincters, and first order capillaries, is the bottleneck for brain blood flow and energy …

Введение. Все большая значимость исследований головного мозга требует знания
анатомического строения головного мозга крысы-наиболее часто используемого …