Alginate as an immobilization material for MAb production via encapsulated hybridoma cells
SM Selimoglu, M Elibol - Critical reviews in biotechnology, 2010 - Taylor & Francis
Alginate has been widely used in various applications since its first extraction. What makes
this biopolymer useful is its high biocompatibility and humid gelation conditions. Both of …
this biopolymer useful is its high biocompatibility and humid gelation conditions. Both of …
Alginate bead fabrication and encapsulation of living cells under centrifugally induced artificial gravity conditions
S Haeberle, L Naegele, R Burger, F Stetten… - Journal of …, 2008 - Taylor & Francis
This study presents a novel method for the direct, centrifugally induced fabrication of small,
Ca2+-hardened alginate beads at polymer-tube micronozzles. The bead diameter can …
Ca2+-hardened alginate beads at polymer-tube micronozzles. The bead diameter can …
Nutrient capsules maintain tear film homeostasis for human corneal lenticule transplantation
J Zhao, Z Zhang, F Xia, G Li, Q Saiding, L Xiang… - Chemical Engineering …, 2022 - Elsevier
Corneal lenticule transplantation can be applied in the correction of refractive errors and
various corneal diseases. However, current techniques to preserve cornea are limited due to …
various corneal diseases. However, current techniques to preserve cornea are limited due to …
Immobilized enzymes and cells in poly(N-vinyl caprolactam)-based hydrogels: Preparation, properties, and applications in biotechnology and medicine
EA Markvicheva, SV Kuptsova, TY Mareeva… - Applied biochemistry …, 2000 - Springer
A one-step mild method for entrapping animal cells and enzymes in macroporous composite
poly (N-vinyl caprolactam)-calcium alginate (PVCL-CaAlg) hydrogels is described. Some …
poly (N-vinyl caprolactam)-calcium alginate (PVCL-CaAlg) hydrogels is described. Some …
Validation of a novel perfusion bioreactor system in cancer research
J Stojkovska, J Zvicer, M Milivojević, I Petrović… - Hemijska …, 2020 - doiserbia.nb.rs
Development of drugs is a complex, time-and cost-consuming process due to the lack of
standardized and reliable characterization techniques and models. Traditionally, drug …
standardized and reliable characterization techniques and models. Traditionally, drug …
Stability of antibody productivity is improved when hybridoma cells are entrapped in calcium alginate beads
GM Lee, BO Palsson - Biotechnology and bioengineering, 1993 - Wiley Online Library
Loss of monoclonal antibody (MAb) productivity in long‐term, free‐suspended cell culture is
often attributed to the appearance of a nonproducing population of hybridoma cell (NP) in …
often attributed to the appearance of a nonproducing population of hybridoma cell (NP) in …
Cell culture conditions determine the enhancement of specific monoclonal antibody productivity of calcium alginate‐entrapped S3H5/γ2bA2 hybridoma cells
GM Lee, AS Chuck, BO Palsson - Biotechnology and …, 1993 - Wiley Online Library
Immobilization offers several intrinsic advantages over free suspension cultures for the
production of monoclonal antibodies. An important advantage of immobilization is the …
production of monoclonal antibodies. An important advantage of immobilization is the …
Batik Dye Decolorization by Immobilized Biomass of Aspergillus sp
The rapidity of the batik industry in the Former Residence of Banyumas raises problems.
Wastewater that discharged into upstream causes accumulation in downstream up to …
Wastewater that discharged into upstream causes accumulation in downstream up to …
A thermosensitive gel matrix for bioreactor-assisted in-cell NMR of nucleic acids and proteins
M Dzurov, Š Pospíšilová, M Krafčíková… - Journal of biomolecular …, 2023 - Springer
Introducing the flow through the bioreactor has revolutionized in-cell NMR spectroscopy by
prolonging the measurement time available to acquire spectral information about …
prolonging the measurement time available to acquire spectral information about …
Enhancement of monoclonal antibody production by immobilized hybridoma cell culture with hyperosmolar medium
SY Park, GM Lee - Biotechnology and bioengineering, 1995 - Wiley Online Library
To determine the effect of hyperosmotic stress on the monoclonal antibody (MAb) production
by calcium‐alginate‐immobilized S3H5/γ2bA2 hybridoma cells, the osmolalities of medium …
by calcium‐alginate‐immobilized S3H5/γ2bA2 hybridoma cells, the osmolalities of medium …