Accumulating evidence indicates that most primary Wharton's jelly mesenchymal stem cells
(WJ-MSCs) therapeutic potential is due to their paracrine activity, ie, their ability to modulate …

The burden of lung diseases is gradually increasing with an increase in the average human
life expectancy. Therefore, it is necessary to identify effective methods to treat lung diseases …

Over the past few decades, the application of mesenchymal stem cells has captured the
attention of researchers and practitioners worldwide. These cells can be obtained from …

Advances in stem cell (SC) technology allow the generation of cellular models that
recapitulate the histological, molecular and physiological properties of humanized in vitro …

Objective. Although human induced pluripotent stem cell (iPSC)-derived cell replacement for
Parkinson's disease has considerable reparative potential, its full therapeutic benefit is …

Fibrodysplasia ossificans progressiva (FOP) is an enigmatic, ultra-rare genetic disorder
characterized by progressive heterotopic ossification, wherein soft connective tissues …

Vascular dementia (VD) is a prevalent cognitive disorder among the elderly. Its pathological
mechanism encompasses neuronal damage, synaptic dysfunction, vascular abnormalities …

Exosomes, lipid bilayer-enclosed small cellular vesicles, are actively secreted by various
cells and play crucial roles in intercellular communication. These nanosized vesicles …

Background Radiation therapy is the standard of care for central nervous system tumours.
Despite the success of radiation therapy in reducing tumour mass, irradiation (IR)-induced …

Tissue-engineered constructs can replicate the structural and physiological properties of
natural tissues. The constructs can be designed to address the transplantation issues …