Networks of molecular regulators are often the primary objects of focus in the study of gene
regulation, with the machinery of protein synthesis tacitly relegated to the background …

Coupled transcription-translation (CTT) is a hallmark of prokaryotic gene expression. CTT
occurs when ribosomes associate with and initiate translation of mRNAs whose transcription …

A classic problem in microbiology is that bacteria display two types of growth behavior when
cultured on a mixture of two carbon sources: the two sources are sequentially consumed …

Many cellular activities in bacteria are organized according to their growth rate. The notion
that ppGpp measures the cell's growth rate is well accepted in the field of bacterial …

How bacteria link their growth rate to external nutrient conditions is unknown. To investigate
how Bacillus subtilis cells alter the rate at which they expand their cell walls as they grow …

Fitness of bacteria is determined both by how fast cells grow when nutrients are abundant
and by how well they survive when conditions worsen. Here, we study how prior growth …

Our understanding of complex living systems is limited by our capacity to perform
experiments in high throughput. While robotic systems have automated many traditional …

Growth and environmental responses are essential for living organisms to survive and adapt
to constantly changing environments. In order to simulate new conditions and capture …

Ribosome and protein synthesis lie at the core of cell growth and are major consumers of
the cellular budget. Here we review recent progress in the coupling of ribosome synthesis …

Since Jacques Monod's foundational work in the 1940s, investigators studying bacterial
physiology have largely (but not exclusively) focused on the exponential phase of bacterial …