Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes

S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

Weak polyelectrolytes as nanoarchitectonic design tools for functional materials: a review of recent achievements

NM Sanchez-Ballester, F Sciortino, SH Mir, G Rydzek - Molecules, 2022 - mdpi.com
The ionization degree, charge density, and conformation of weak polyelectrolytes can be
adjusted through adjusting the pH and ionic strength stimuli. Such polymers thus offer a …

[HTML][HTML] Innovative chitosan-polyacrylic acid-MoS2 nanocomposite for enhanced and pH-responsive quercetin delivery

M Pourmadadi, H Abdouss, A Memarzadeh… - Materials Today …, 2024 - Elsevier
Cancer remains a global health challenge, with current treatments often leading to adverse
side effects. Herein, a pH-sensitive, biocompatible nanocomposite composed of chitosan …

Hyaluronan/diethylaminoethyl chitosan polyelectrolyte complexes as carriers for improved colistin delivery

NV Dubashynskaya, SV Raik, YA Dubrovskii… - International journal of …, 2021 - mdpi.com
Improving the therapeutic characteristics of antibiotics is an effective strategy for controlling
the growth of multidrug-resistant Gram-negative microorganisms. The purpose of this study …

Synthesis of anionic nanogels for selective and efficient enzyme encapsulation

J Ni, Y Wan, Y Cai, P Ding, MA Cohen Stuart, J Wang - Langmuir, 2022 - ACS Publications
Polyelectrolyte nanogels containing cross-linked ionic polymer networks feature both soft
environment and intrinsic charges which are of great potential for enzyme encapsulation. In …

Revisiting the cytotoxicity of cationic polyelectrolytes as a principal component in layer-by-layer assembly fabrication

E Naumenko, F Akhatova, E Rozhina, R Fakhrullin - Pharmaceutics, 2021 - mdpi.com
Polycations are an essential part of layer-by-layer (LbL)-assembled drug delivery systems,
especially for gene delivery. In addition, they are used for other related applications, such as …

Star Polyelectrolytes with Mixed Arms of PDMAEMA and POEGMA: Self‐Assembly and Coassembly with Insulin

E Vlassi, A Papagiannopoulos… - … Chemistry and Physics, 2022 - Wiley Online Library
Star copolymers with mixed polyelectrolyte/hydrophilic arms of poly (2‐(dimethylamino) ethyl
methacrylate)(PDMAEMA) and poly (oligo (ethylene glycol) methyl ether methacrylate) …

Nanofibrous composite from chitosan-casein polyelectrolyte complex for rapid hemostasis in rat models in vivo

B Mishra, D Pathak, D Verma, MK Gupta - International Journal of …, 2024 - Elsevier
Bleeding causes∼ 5.8 million deaths globally; half of the patients die if rapid hemostasis is
not achieved. Here, we report a chitosan-casein (CC)-based nanofibrous polyelectrolyte …

Hyaluronan/B12-chitosan polyelectrolyte complex for oral colistin administration

NV Dubashynskaya, AN Bokatyi, TS Sall… - International Journal of …, 2024 - Elsevier
Polyelectrolyte complexes (PECs) based on polysaccharides, including hyaluronic acid (HA)
and chitosan (CS), are promising delivery systems for antimicrobial agents, including oral …

Complexation of poly (methacrylic acid) star polyelectrolytes with lysozyme

D Fotaki, M Karayianni, A Skandalis, E Haladjova… - European Polymer …, 2024 - Elsevier
Protein-polyelectrolyte complexes are of great interest due to their applications in both
biological and industrial systems. This study focuses on investigating the electrostatic …