Epidemiology of sepsis and septic shock

C Chiu, M Legrand - Current Opinion in Anesthesiology, 2021 - journals.lww.com
Epidemiology of sepsis and septic shock : Current Opinion in Anesthesiology Epidemiology of
sepsis and septic shock : Current Opinion in Anesthesiology Log in or Register Subscribe to …

Blood culture utilization in the hospital setting: a call for diagnostic stewardship

V Fabre, KC Carroll, SE Cosgrove - Journal of clinical …, 2022 - Am Soc Microbiol
There has been significant progress in detection of bloodstream pathogens in recent
decades with the development of more sensitive automated blood culture detection systems …

Prospective, multi-site study of patient outcomes after implementation of the TREWS machine learning-based early warning system for sepsis

R Adams, KE Henry, A Sridharan, H Soleimani… - Nature medicine, 2022 - nature.com
Early recognition and treatment of sepsis are linked to improved patient outcomes. Machine
learning-based early warning systems may reduce the time to recognition, but few systems …

Factors driving provider adoption of the TREWS machine learning-based early warning system and its effects on sepsis treatment timing

KE Henry, R Adams, C Parent, H Soleimani… - Nature medicine, 2022 - nature.com
Abstract Machine learning-based clinical decision support tools for sepsis create
opportunities to identify at-risk patients and initiate treatments at early time points, which is …

Prevalence of co-infection at the time of hospital admission in COVID-19 patients, a multicenter study

SM Karaba, G Jones, T Helsel, LL Smith… - Open forum …, 2021 - academic.oup.com
Background Bacterial infections may complicate viral pneumonias. Recent reports suggest
that bacterial co-infection at time of presentation is uncommon in coronavirus disease 2019 …

Time-to-antibiotics and clinical outcomes in patients with sepsis and septic shock: a prospective nationwide multicenter cohort study

Y Im, D Kang, RE Ko, YJ Lee, SY Lim, S Park, SJ Na… - Critical Care, 2022 - Springer
Background Timely administration of antibiotics is one of the most important interventions in
reducing mortality in sepsis. However, administering antibiotics within a strict time threshold …

Association between time to appropriate antimicrobial treatment and 30-day mortality in patients with bloodstream infections: a retrospective cohort study

J Van Heuverswyn, JK Valik… - Clinical infectious …, 2023 - academic.oup.com
Background Effective antimicrobial treatment is key for survival in bloodstream infection
(BSI), but the impact of timing of treatment remains unclear. Our aim was to assess the …

Association between implementation of the severe sepsis and septic shock early management bundle performance measure and outcomes in patients with suspected …

C Rhee, T Yu, R Wang, SS Kadri, D Fram… - JAMA network …, 2021 - jamanetwork.com
Importance In October 2015, the Centers for Medicare & Medicaid Services began requiring
US hospitals to report adherence to the Severe Sepsis and Septic Shock Early Management …

Risk of misleading conclusions in observational studies of time-to-antibiotics and mortality in suspected sepsis

TR Pak, J Young, CS McKenna, A Agan… - Clinical Infectious …, 2023 - academic.oup.com
Background Influential studies conclude that each hour until antibiotics increases mortality in
sepsis. However, these analyses often (1) adjusted for limited covariates,(2) included …

Treatment patterns and clinical outcomes after the introduction of the Medicare sepsis performance measure (SEP-1)

IJ Barbash, BS Davis, JG Yabes… - Annals of internal …, 2021 - acpjournals.org
Background: Medicare requires that hospitals report on their adherence to the Severe
Sepsis and Septic Shock Early Management Bundle (SEP-1). Objective: To evaluate the …