[HTML][HTML] Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

[HTML][HTML] Vascular dysfunction in preeclampsia

MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …

Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta …

FJK Toloza, A Derakhshan, T Männistö… - The Lancet Diabetes & …, 2022 - thelancet.com
Background Adequate maternal thyroid function is important for an uncomplicated
pregnancy. Although multiple observational studies have evaluated the association between …

[HTML][HTML] IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Cell-free DNA methylome analysis for early preeclampsia prediction

M De Borre, H Che, Q Yu, L Lannoo, K De Ridder… - Nature Medicine, 2023 - nature.com
Preeclampsia (PE) is a leading cause for peripartal morbidity, especially if developing early
in gestation. To enable prophylaxis in the prevention of PE, pregnancies at risk of PE must …

The role of immune cells and mediators in preeclampsia

E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023 - nature.com
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …

[HTML][HTML] Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice

J Hu, X Qin, J Zhang, Y Zhu, W Zeng, Y Lin… - Reproductive Toxicology, 2021 - Elsevier
Microplastics (MPs), which are emerging as a new type of environmental pollutants, have
raised great concerns regarding their threats to human health. A successful pregnancy …

[HTML][HTML] Distinct placental molecular processes associated with early-onset and late-onset preeclampsia

Z Ren, Y Gao, Y Gao, G Liang, Q Chen, S Jiang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Patients with preeclampsia display a spectrum of onset time and severity of
clinical presentation, yet the underlying molecular bases for the early-onset and late-onset …

[HTML][HTML] Extracellular vesicles from mesenchymal stromal cells for the treatment of inflammation-related conditions

ST Ryan, E Hosseini-Beheshti, D Afrose… - International Journal of …, 2021 - mdpi.com
Over the past two decades, mesenchymal stromal cells (MSCs) have demonstrated great
potential in the treatment of inflammation-related conditions. Numerous early stage clinical …

[HTML][HTML] Exposure to microplastics during early developmental stage: review of current evidence

NH Amran, SSM Zaid, MH Mokhtar, LA Manaf… - Toxics, 2022 - mdpi.com
In the last few decades, microplastics (MPs) have been among the emerging environmental
pollutants that have received serious attention from scientists and the general population …