Background The three primary headaches, tension-type headache, migraine and cluster
headache, occur in both genders, but all seem to have a sex-specific prevalence. These …

Migraine is a major neurological disorder affecting one in nine adults worldwide with a
significant impact on health care and socioeconomic systems. Migraine is more prevalent in …

Objective To explore and critically appraise the evidence supporting the role of estrogen
withdrawal in menstrual migraine. Main body Menstrual migraine, impacting about 6% of …

Introduction The mechanism of action of non-invasive vagal nerve stimulation in the
treatment of migraine is elusive. We studied its effect in a human model of pain, the …

The incidence of migraine is higher in women than in men. Abnormality of the hypothalamus-
pituitary-gonadal (HPG) axis is believed to be implicated in the pathogenesis of migraine …

Objective To examine the longitudinal course of vasomotor symptoms (VMS) in women with
a history of migraine in comparison to women without a history of migraine disease. Methods …

Together with the nociceptive system, pain protects the body from tissue damage. For
instance, when the RIII-reflex is evoked by sural nerve stimulation, nociceptive inputs …

Introduction Estrogen fluctuations modulate pain threshold and play a pivotal role in the
central and peripheral pathogenesis of menstrually related migraine (MRM). Estrogen …

The nitric-oxide donor nitroglycerin (NTG) administration induces a facilitation of nociceptive
pathways in episodic migraine. This study aims to test the hypothesis that induced spinal …

Inability of habituation is a phenomenon whereby droop responses of cortical responses to
repetitive sensory stimulation where the amplitude is persistently increased, which results in …