Omics-based biomarkers for the early Alzheimer disease diagnosis and reliable therapeutic targets development

C Peña-Bautista, M Baquero, M Vento… - Current …, 2019 - ingentaconnect.com
Background: Alzheimer's disease (AD), the most common cause of dementia in adulthood,
has great medical, social, and economic impact worldwide. Available treatments result in …

[HTML][HTML] Sex differences in the metabolome of Alzheimer's disease progression

T González Zarzar, B Lee, R Coughlin, D Kim… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the leading cause of dementia; however, men and women face
differential AD prevalence, presentation, and progression risks. Characterizing metabolomic …

Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression

K Nho, A Kueider-Paisley, M Arnold… - Brain …, 2021 - academic.oup.com
Metabolomics in the Alzheimer's Disease Neuroimaging Initiative cohort provides a powerful
tool for mapping biochemical changes in Alzheimer's disease, and a unique opportunity to …

SPARCL1 accelerates symptom onset in Alzheimer's disease and influences brain structure and function during aging

S Seddighi, VR Varma, Y An, S Varma… - Journal of …, 2018 - content.iospress.com
We recently reported that alpha-2 macroglobulin (A2M) is a biomarker of neuronal injury in
Alzheimer's disease (AD) and identified a network of nine genes co-expressed with A2M in …

[HTML][HTML] Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts

L St. John-Williams, S Mahmoudiandehkordi, M Arnold… - Scientific data, 2019 - nature.com
Alzheimer's disease (AD) is the most common cause of dementia. The mechanism of
disease development and progression is not well understood, but increasing evidence …

[HTML][HTML] Apolipoprotein E polymorphisms increase the risk of post-stroke depression

X Li, J Wang, A Xu, J Huang, L Meng… - Neural regeneration …, 2016 - journals.lww.com
Recent reports have shown that apolipoprotein E (APOE) polymorphisms are involved in
neurodegenerative disease. However, it is unclear whether APOE affects post-stroke …

[HTML][HTML] Correlation between mild cognitive impairment and sarcopenia: the prospective role of lipids and basal metabolic rate in the link

X Wang, R Xiao, H Li, T Li, L Guan, H Ding, X Li… - Nutrients, 2022 - mdpi.com
There is evidence of correlation between mild cognitive impairment (MCI) and sarcopenia
(SA). However, the influencing factors and the mechanism, such as age-related lipid …

不同运动方式对大脑结构及认知功能的调节作用及差异

路毅, 邓文冲 - 中国组织工程研究, 2021 - cjter.com
不同运动方式对大脑结构及认知功能的调节作用及差异 Page 1 3252 |中国组织工程研究|第25卷
|第20期|2021年7月 不同运动方式对大脑结构及认知功能的调节作用及差异 路毅,邓文冲 文题释义 …

Lecithin (Phosphatidylcholine): Healthy dietary supplement or dangerous toxin?

RE Smith, P Rouchotas, H Fritz - The Natural Products Journal, 2016 - ingentaconnect.com
Phosphatidylcholine (PC) is an essential part of human cell membranes and an important
dietary source of choline, an important biochemical. Its common name is lecithin. It can be …

Combined metabolic activators improves cognitive functions in Alzheimer's disease

B Yulug, O Altay, X Li, L Hanoglu, S Cankaya, S Lam… - MedRxiv, 2021 - medrxiv.org
Alzheimer's disease (AD) is associated with metabolic abnormalities linked to critical
elements of neurodegeneration. Here, we analysed the brain transcriptomics data of more …