The long and short non-coding RNAs modulating EZH2 signaling in cancer

S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

Long noncoding RNAs (lncRNAs) in pancreatic cancer progression

M Ashrafizadeh, N Rabiee, AP Kumar, G Sethi… - Drug discovery today, 2022 - Elsevier
Long noncoding RNAs (lncRNAs) are RNA molecules involved in gene regulation at
transcriptional, post-transcriptional, and epigenetic levels. LncRNAs participate in regulating …

[HTML][HTML] Histone methylation in pancreatic cancer and its clinical implications

XY Liu, CH Guo, ZY Xi, XQ Xu, QY Zhao… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is an aggressive human cancer. Appropriate methods for the
diagnosis and treatment of PC have not been found at the genetic level, thus making …

[HTML][HTML] MicroRNAs and long non-coding RNAs in pancreatic cancer: From epigenetics to potential clinical applications

LA Bravo-Vázquez, N Frías-Reid… - Translational …, 2023 - Elsevier
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two relevant classes of non-
coding RNAs (ncRNAs) that play a pivotal role in a number of molecular processes through …

LINC00114 stimulates growth and glycolysis of esophageal cancer cells by recruiting EZH2 to enhance H3K27me3 of DLC1

J Qin, Y Li, Z Li, X Qin, X Zhou, H Zhang, S Li - Clinical epigenetics, 2022 - Springer
Objective LINC00114 could promote the development of colorectal cancer, but its
mechanism has been rarely discussed in esophageal cancer (EC). Herein, we explored the …

A reciprocal feedback between N6-methyladenosine reader YTHDF3 and lncRNA DICER1-AS1 promotes glycolysis of pancreatic cancer through inhibiting maturation …

Y Hu, J Tang, F Xu, J Chen, Z Zeng, S Han… - Journal of Experimental …, 2022 - Springer
Background Glycolysis is a pivotal process in metabolic reprogramming of tumorigenesis.
Previous research has indicated that lncRNAs might play crucial roles in glycolysis of …

A glycolysis-based long non-coding RNA signature accurately predicts prognosis in renal carcinoma patients

H Cao, H Tong, J Zhu, C Xie, Z Qin, T Li, X Liu… - Frontiers in …, 2021 - frontiersin.org
Background The prognosis of renal cell carcinoma (RCC) varies greatly among different risk
groups, and the traditional indicators have limited effect in the identification of risk grade in …

An overview of epigenetic methylation in pancreatic cancer progression

Y Zhao, M Yang, S Wang, SJ Abbas, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Over the past decades, the aberrant epigenetic modification, apart from genetic alteration,
has emerged as dispensable events mediating the transformation of pancreatic cancer (PC) …

Glycometabolic rearrangements–aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC): roles, regulatory networks, and therapeutic potential

Z Zhang, HJ Zhang - Expert opinion on therapeutic targets, 2021 - Taylor & Francis
Introduction Glycometabolic rearrangements (aerobic glycolysis) is a hallmark of pancreatic
ductal adenocarcinoma (PDAC) and contributes to tumorigenesis and progression through …

Long non-coding RNAs associated with mitogen-activated protein kinase in human pancreatic cancer

T Ishikawa, S Fukushige, Y Saiki, K Hirose, T Hiyoshi… - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNAs) have emerged as a significant player in
various cancers, including pancreatic cancer. However, how lncRNAs are aberrantly …