Heart disease is the leading cause of death worldwide. Cardiomyopathy is a disease
characterized by the heart muscle damage, resulting heart in a structurally and functionally …

Cardiovascular disease (CVD) accounts for the largest number of deaths worldwide,
necessitating the development of novel treatments and prevention strategies. Given the …

The WNT/β‐catenin pathway is a master regulator of cardiac development and growth, and
its activity is low in healthy adult hearts. However, even this low activity is essential for …

Although cardiac fibrosis causes heart failure, its molecular mechanisms remain elusive. In
this study, we investigated the mechanisms of cardiac fibrosis and examined the effects of …

Dietary selenium (Se) is an essential micronutrient that exerts its biological effects through
its incorporation into selenoproteins. This family of proteins contains several antioxidant …

The effect of a single one-hour exposure to three modes of hypobaric hypoxia (HBH) differed
in the content of O2 in inhaled air (FiO2—14%, 10%, 8%) in the development of …

Met, the tyrosine kinase receptor for hepatocyte growth factor (HGF), mainly activates
prosurvival pathways, including protection from apoptosis. In this work, we investigated the …

Recent studies suggest that the dysfunction of neural plasticity is associated with mood
disorders. Hypoxia-inducible factor-1 (HIF-1), which is a transcriptional activator of vascular …

Abstract Background Galectin-3 (GAL-3) plays a regulatory role in several diverse biological
processes and disease states. It is associated with heart failure and increased risk of death …

Background Myocardial ischemia–reperfusion (IR) injury is a damage due to an initial
reduction in blood flow to the heart, preventing it from receiving enough oxygen, and …