The extracellular matrix (ECM) consists of a complex mixture of structural and functional
proteins and serves an important role in tissue and organ morphogenesis, maintenance of …

Bioscaffolds derived from xenogeneic extracellular matrix (ECM) have been used in
numerous tissue engineering applications. The safety and efficacy of such scaffolds when …

Biological scaffolds composed of extracellular matrix (ECM) have been shown to be
resistant to deliberate bacterial contamination in preclinical in vivo studies. The present …

The aim of this study was to produce a natural, acellular matrix from porcine bladder tissue
for use as a scaffold in developing a tissue-engineered bladder replacement. Full-thickness …

We have investigated the use of natural and synthetic collagenous matrices as carriers of
exogenous growth factors. A bladder acellular matrix (BAM) was processed from rat bladder …

Human adipose stem cells were cultured in smooth muscle inductive media and seeded into
synthetic bladder composites to tissue engineer bladder smooth muscle. 85: 15 Poly-lactic …

The rate of in vivo degradation was determined for a naturally occurring biomaterial derived
from the extracellular matrix of the small intestinal submucosa (SIS). The SIS was labeled by …

Current strategies for engineering bladder tissues include a bladder biopsy for in vitro cell
expansion for use in reconstructive procedures. However, this approach cannot be used in …

The principles and ultimate goals of regenerative medicine and developmental biology
involve a complex sequence of events, culminating in the formation of structurally and …

Bladder regeneration studies have yielded inconclusive results possibly due to the use of
unfavorable cells and primitive scaffold design. We hypothesized that human mesenchymal …