Pancreatic cancer is a highly lethal form of digestive malignancy that poses significant
health risks to individuals worldwide. Chemotherapy‐based comprehensive treatment is the …

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. It
has a poor response to conventional therapy and has an extremely poor 5-year survival rate …

Cancer is a malignant disease that endangers human life, especially owing to its high fatality
rate; therefore, rapid and accurate early screening is needed to effectively improve the …

Pigs are playing an increasingly vital role as translational biomedical models for studying
human pathophysiology. The annotation of the pig genome was a huge step forward in …

Introduction Pancreatic ductal adenocarcinoma presents with a dismal prognosis.
Personalized therapy is urgently warranted to overcome the treatment limitations of the 'one …

Background The reactivation of genetic programs from early development is a common
mechanism for injury-induced organ regeneration. T-box 3 (TBX3) is a member of the T-box …

As one of the deadliest cancers, pancreatic ductal adenocarcinoma (PDAC) requires
sophisticated model systems to dissect disease onset, progression, and therapy resistance …

Ex vivo organ culture can be a useful alternative to in vivo models, which can be time-, labor-
, and cost-intensive. Here we describe a step-by-step protocol to use de-epithelialized …

Zusammenfassung Hintergrund Die Therapieoptionen beim lokal fortgeschrittenen und
metastasierten Urothelkarzinom beschränken sich aktuell auf etablierte Chemo-sowie …