In response to infection, naive CD 4+ T‐cells proliferate and differentiate into several
possible effector subsets, including conventional T helper effector cells (TH 1, TH 2, TH 17) …

Immunologic memory is the adaptive immune system's powerful ability to remember a
previous antigen encounter and react with accelerated vigor upon antigen re-exposure. It …

Self-assembling peptides and peptide derivatives have received significant interest for
several biomedical applications, including tissue engineering, wound healing, cell delivery …

CLEC9A is a recently discovered C-type lectin receptor involved in sensing necrotic cells. In
humans, this receptor is selectively expressed by BDCA3+ myeloid dendritic cells (mDCs) …

Over the past several years, there have been remarkable advances in our understanding of
how commensal organisms shape host immunity. Although the full cast of immunogenic …

As a newly identified type of programmed cell death, cuproptosis may have an impact on
cancer development, including clear cell renal cell carcinoma (ccRCC). Herein, we first …

Tissue‐resident memory T cells (TRMs) are plentiful in the memory T cell pool and persist in
barrier sites without recirculating. Increasing evidence has shown that some kinds of CD8+ …

CD4 T cell help for B cells is critical for effective Ab responses. Although many of the
molecules involved in helper functions of naive CD4 T cells have been characterized, much …

CD4+ memory/effector T cells play a central role in orchestrating the rapid and robust
immune responses upon re-encounter with specific Ags. However, the immunologic …

The importance of CD4 T cells in orchestrating the immune system and their role in inducing
effective T cell-mediated therapies for the treatment of patients with select established …