Near-infrared (NIR) spectroscopy is a powerful analytical method for rapid, non-destructive
and label-free assessment of biological materials. Compared to mid-infrared spectroscopy …

This review describes recent developments and applications of near-infrared (NIR)
spectroscopy for characterization of articular cartilage integrity. It summarizes the research …

Degenerative joint conditions are often characterized by changes in articular cartilage and
subchondral bone properties. These changes are often associated with subchondral plate …

This study evaluates the feasibility of near infrared (NIR) spectroscopy to distinguish
between different cartilage injury types associated with post-traumatic osteoarthritis and …

Osteoarthritis (OA) is a chronic joint disease and hard to cure at present. Alpha B-crystallin
(CRYAB) has been identified as a downregulated gene in OA cartilage. However, the …

Objective Spectroscopic techniques, such as near-infrared (NIR) spectroscopy, are gaining
significant research interest for characterizing connective tissues, particularly articular …

The conventional mechanical properties of articular cartilage, such as compressive stiffness,
have been shown to have limited capacity to distinguish visually normal from degraded …

Arthroscopic evaluation of post-traumatic osteoarthritis (PTOA) is limited and subjective with
the current diagnostic techniques visual evaluation and tissue palpation. Reliable evaluation …

Articular cartilage, the soft tissue covering the ends of articulating bones, facilitates smooth
joint movements. This specialized connective tissue is avascular and aneural, with limited …