The recent advent of transition‐metal mediated C H activation is revolutionizing the
synthetic field and gradually infusing a “C H activation mind‐set” in both students and …

Plant in vitro cultures are able to produce and accumulate many medicinally valuable
secondary metabolites. Antioxidants are an important group of medicinal preventive …

Lignans are phenylpropanoid dimers, where the phenylpropane units are linked by the
central carbon (C8) of their side chains. Ligans vary substantially in oxidation level …

Modern lifestyle factors, such as physical inactivity, obesity, smoking, and exposure to
environmental pollution, induce excessive generation of free radicals and reactive oxygen …

Rosmarinic acid (RA) is one of the first secondary metabolites produced in plant cell cultures
in extremely high yields, up to 19% of the cell dry weight. More complex derivatives of RA …

The total synthesis of (+)-lithospermic acid is described. The efficient synthesis features an
asymmetric alkylation via C− H bond activation to assemble the dihydrobenzofuran core of …

Lithospermum erythrorhizon cell cultures have been used to produce plant secondary
metabolites, as well as in biosynthetic studies. Shikonin, a representative secondary …

Two cDNAs encoding geranyl diphosphate: 4-hy-droxybenzoate 3-geranyltransferase were
isolated fromLithospermum erythrorhizon by nested PCR using the conserved amino acid …

Biotechnology approaches applied through plant tissue culture of milk thistle (Silybum
marianum L. Gaertn.) can contribute to the production of biologically active substances …

Caffeic acid is a phenylpropanoid playing an important role in the pathways leading to lignin
synthesis and the production of a wide variety of secondary metabolites. The compound is …