Ulcerative colitis and Crohn's disease are the 2 major phenotypes of inflammatory bowel
disease (IBD), which are influenced by a complex interplay of immunological and genetic …

BACKGROUND: Psoriasis is a chronic autoimmune hyperproliferative skin disease of
varying severity affecting approximately 2–3% of the general population in the USA and …

Dry eye is an inflammatory disease that results from activation of innate inflammatory
pathways in resident ocular surface cells, as well as cytokines produced by recruited T …

The mammalian intestine is the largest immune organ that contains the intestinal stem cells
(ISC), differentiated epithelial cells (enterocytes, Paneth cells, goblet cells, tuft cells, etc.) …

Hereditary haemophagocytic lymphohistiocytosis (HLH) is a fatal inflammatory disease and
treatments currently may lead to serious side effects. There is a pressing need for effective …

To the Editor: Psoriasis is a chronic inflammatory skin disease in which epidermal
hyperplasia occurs because of skin infiltration of activated immune cells. TH1 cells, defined …

The food colorant Red 40 is an environmental risk factor for colitis development in mice with
increased expression of interleukin (IL)-23. This immune response is mediated by CD4+ T …

Inflammatory bowel diseases (IBDs) are characterized by chronic inflammatory disorders
that are a result of an abnormal immune response mediated by a cytokine storm and …

Graft vascular disease (GVD) is the single most important long-term limitation to solid-organ
transplantation. It is a concentric vascular intimal hyperplastic lesion composed of smooth …

During the last decade, biological therapies have an increasing share in the modern
therapeutics of various diseases including inflammatory bowel diseases (IBD). Animal …