Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

The prevalence of type 2 diabetes mellitus is increasing in both sexes, but men are usually
diagnosed at a younger age and lower body fat mass than women. Worldwide, an estimated …

Adipose tissue is the largest endocrine organ and an accepted contributor to overall energy
homeostasis. There is strong evidence linking increased adiposity to the development of 13 …

Although promising therapeutics are in the pipeline, bariatric surgery (also known as
metabolic surgery) remains our most effective strategy for the treatment of obesity and type 2 …

Prevention of common diseases of the pancreas or interception of their progression is as
attractive in theory as it is elusive in practice. The fundamental challenge has been an …

Fat accumulation in the liver, pancreas, skeletal muscle, and visceral bed relates to type 2
diabetes (T2D). However, the distribution of fat among these compartments is heterogenous …

The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …

Pancreatic ductal adenocarcinoma (PDAC) can be treated with surgery, chemotherapy, and
radiotherapy. Despite medical progress in each field in recent years, it is still insufficient for …

Fatty infiltration of the pancreas (FIP) has been recognized for nearly a century, yet many
aspects of this condition remain unclear. Regular literature reviews on the diagnosis …

Background A number of recent observational studies have indicated a correlation between
the constitution of gut microbiota and the incidence of pancreatitis. Notwithstanding …