Endothelial and microcirculatory function and dysfunction in sepsis
JF Colbert, EP Schmidt - Clinics in chest medicine, 2016 - chestmed.theclinics.com
The microcirculation, comprised of less than 100 μm–diameter arterioles, capillary beds, and
draining venules, performs essential homeostatic functions, including oxygen delivery and …
draining venules, performs essential homeostatic functions, including oxygen delivery and …
Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability
M Nieuwdorp, MC Meuwese… - Journal of applied …, 2008 - journals.physiology.org
The endothelial glycocalyx is increasingly considered as an intravascular compartment that
protects the vessel wall against pathogenic insults. The purpose of this study was to …
protects the vessel wall against pathogenic insults. The purpose of this study was to …
The endothelial glycocalyx as a barrier to leukocyte adhesion and its mediation by extracellular proteases
HH Lipowsky - Annals of biomedical engineering, 2012 - Springer
The endothelial cell (EC) surface is coated with a layer of polysaccharides linked to
membrane-bound and trans-membrane proteoglycans that comprise the glycocalyx, which …
membrane-bound and trans-membrane proteoglycans that comprise the glycocalyx, which …
Evaluation of resuscitation fluids on endothelial glycocalyx, venular blood flow, and coagulation function after hemorrhagic shock in rats
BACKGROUND Endothelial glycocalyx (EG) plays an essential role in endothelium integrity
and may be compromised by hemorrhagic shock. The effects of currently available …
and may be compromised by hemorrhagic shock. The effects of currently available …
The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness
D Chappell, M Westphal, M Jacob - Current Opinion in …, 2009 - journals.lww.com
The impact of the glycocalyx on microcirculatory oxygen dist... : Current Opinion in
Anesthesiology The impact of the glycocalyx on microcirculatory oxygen distribution in critical …
Anesthesiology The impact of the glycocalyx on microcirculatory oxygen distribution in critical …
Endothelial activation and microcirculatory disorders in sepsis
L Raia, L Zafrani - Frontiers in Medicine, 2022 - frontiersin.org
The vascular endothelium is crucial for the maintenance of vascular homeostasis. Moreover,
in sepsis, endothelial cells can acquire new properties and actively participate in the host's …
in sepsis, endothelial cells can acquire new properties and actively participate in the host's …
Advanced age results in a diminished endothelial glycocalyx
DR Machin, SI Bloom, RA Campbell… - American Journal …, 2018 - journals.physiology.org
Age-related microvascular dysfunction is well characterized in rodents and humans, but little
is known about the properties of the microvascular endothelial glycocalyx in advanced age …
is known about the properties of the microvascular endothelial glycocalyx in advanced age …
Peritubular capillary rarefaction: an underappreciated regulator of CKD progression
Y Kida - International Journal of Molecular Sciences, 2020 - mdpi.com
Peritubular capillary (PTC) rarefaction is commonly detected in chronic kidney disease
(CKD) such as hypertensive nephrosclerosis and diabetic nephropathy. Moreover, PTC …
(CKD) such as hypertensive nephrosclerosis and diabetic nephropathy. Moreover, PTC …
Tumor necrosis factor-α inhibition protects against endotoxin-induced endothelial glycocalyx perturbation
M Nieuwdorp, MC Meuwese, HL Mooij… - Atherosclerosis, 2009 - Elsevier
OBJECTIVE: Inflammatory stimuli profoundly increase the vulnerability of the vessel wall to
atherogenesis. The endothelial glycocalyx, a layer of glycosaminoglycans and …
atherogenesis. The endothelial glycocalyx, a layer of glycosaminoglycans and …
Microcirculatory dysfunction in sepsis: pathophysiology, clinical monitoring, and potential therapies
M Miranda, M Balarini, D Caixeta… - American Journal of …, 2016 - journals.physiology.org
Abnormal microvascular perfusion, including decreased functional capillary density and
increased blood flow heterogeneity, is observed in early stages of the systemic inflammatory …
increased blood flow heterogeneity, is observed in early stages of the systemic inflammatory …