Эндотелиальный гликокаликс: методы исследования и перспективы их применения при оценке дисфункции эндотелия

ТД Власов, ОА Лазовская, ДА Шиманьски… - Регионарное …, 2020 - microcirc.ru
Аннотация Современный взгляд на эндотелиальную дисфункцию в патогенезе многих
заболеваний включает, наряду с нарушением морфологии и функции клеток …

Organ dysfunction in cirrhosis: a mechanism involving the microcirculation

A Brito-Azevedo, RM Perez, PA Maranhão… - European Journal of …, 2019 - journals.lww.com
Results Fifty-four patients and 18 controls were included. Inflammatory and endothelial
markers increased in advanced disease. FCD was reduced and RBCA was progressively …

Rapid insulin-mediated increase in microvascular glycocalyx accessibility in skeletal muscle may contribute to insulin-mediated glucose disposal in rats

BJM Eskens, HL Mooij, JPM Cleutjens, JMA Roos… - PLoS …, 2013 - journals.plos.org
It has been demonstrated that insulin-mediated recruitment of microvascular blood volume is
associated with insulin sensitivity. We hypothesize that insulin rapidly stimulates penetration …

[HTML][HTML] The role of exercise in diabetes

SJ Zahalka, LA Abushamat, RL Scalzo, JEB Reusch - 2019 - europepmc.org
Exercise is a key component to lifestyle therapy for prevention and treatment of type 2
diabetes (T2D). These recommendations are based on positive associations between …

Impact of enzymatic degradation of the endothelial glycocalyx on vascular permeability in an awake hamster model

SA Landsverk, AG Tsai, P Cabrales… - Critical care research …, 2012 - Wiley Online Library
Background. The inside of the endothelium is covered by a glycocalyx layer, and enzymatic
degradation of this layer induces vascular leakage ex vivo. We hypothesized that enzymatic …

The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights

M Bender, JM Abicht, B Reichart, M Leuschen, F Wall… - Biomedicines, 2024 - mdpi.com
Cardiac xenotransplantation has seen remarkable success in recent years and is emerging
as the most promising alternative to human cardiac allotransplantation. Despite these …

A conceptual framework for predicting and addressing the consequences of disease‐related microvascular dysfunction

PM McClatchey, JC Frisbee, JEB Reusch - Microcirculation, 2017 - Wiley Online Library
Objective A growing body of evidence indicates that impaired microvascular perfusion plays
a pathological role in a number of diseases. This manuscript aims to better define which …

Plasma hyaluronan, hyaluronidase activity and endogenous hyaluronidase inhibition in sepsis: an experimental and clinical cohort study

J van der Heijden, C Kolliopoulos, P Skorup… - Intensive care medicine …, 2021 - Springer
Background Plasma hyaluronan concentrations are increased during sepsis but underlying
mechanisms leading to high plasma hyaluronan concentration are poorly understood. In this …

Red blood cell storage and adhesion to vascular endothelium under normal or stress conditions: an in vitro microfluidic study

LN Diebel, DM Liberati - Journal of Trauma and Acute Care …, 2019 - journals.lww.com
BACKGROUND Observational studies have identified an association between duration of
red blood cell (RBC) storage and adverse outcomes in trauma. Hemorrhagic shock (HS) …

Blood flow distribution and the endothelial surface layer in the diabetic retina

NR Harris, W Leskova, G Kaur, RS Eshaq… - …, 2019 - content.iospress.com
Diabetic retinopathy is known as a microvascular complication of hyperglycemia, with a
breakdown of the blood-retinal barrier, loss of pericytes, formation of microhemorrhages …