Sepsis is expected to have a substantial impact on public health and cost as its prevalence
increases. Factors contributing to increased prevalence include a progressively aging …

The recent success of PD-1 and PD-L1 blockade in cancer therapy illustrates the important
role of the PD-1/PD-L1 pathway in the regulation of antitumor immune responses. However …

Sepsis is a life-threatening medical condition that occurs when the host has an uncontrolled
or abnormal immune response to overwhelming infection. It is now widely accepted that …

The goal of this study was to conduct a systematic review of the literature on the relationship
between peripheral blood platelet to lymphocyte ratio (PLR) and mortality in sepsis and to …

A central clinical question as the world deals with the COVID-19 pandemic is what the long-
term sequelae for the millions of individuals will be who recover from the hyperinflammatory …

Sepsis is a heterogeneous syndrome comprising a highly diverse and dynamic mixture of
hyperinflammatory and compensatory anti-inflammatory immune responses. This immune …

Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

Introduction In patients with SARS-CoV-2, innate immunity is playing a central role, depicted
by hyperinflammation and longer lasting inflammatory response. Reliable inflammatory …

Sepsis is a leading cause of death in intensive care units and survivors develop prolonged
immunosuppression and a high incidence of recurrent infections. No definitive therapy exists …

Immunosuppression is increasingly being recognized as one of the causes of increased
morbidity and mortality during sepsis. Both innate and adaptive immune system dysfunction …