Objectives: Diabetic polyneuropathy is a serious complication of diabetes mellitus and the
most frequent neuropathy worldwide. Evening primrose oil (EPO) is rich in omega-6 …

Inherited metabolic diseases (IMDs) comprise a diverse group of metabolic conditions
resulting mainly from enzyme deficiencies. IMDs can be classified into three main groups …

OBJECTIVES: Neurotoxic metabolites and oxidative and nitrosative stress reactions play a
crucial role in the pathways leading to neuronal cell death and neurodegeneration. The …

Abstract X-linked adrenoleukodystrophy (X-ALD) is the most frequent peroxisomal disorder,
and is caused by dysfunction of the peroxisomal ABC protein ABCD1. X-ALD patients with …

Demyelinating diseases is common in neurology department, but its treatment is still not
clear. A 40-year-old male who was addicted in heroin was hospitalized and presented …

Peroxisomal disorders (PD) are genetic disorders caused by peroxisome dysfunction and
are classified into two groups: genetic defects in peroxisome-localized proteins and genetic …

The human peroxisome biogenesis disorders (PBD) are caused by autosomal recessive
mutations in any of the 14 PEX genes, which encode peroxins, or PEX proteins, that act …

Peripheral nerve injury (PNI) is a common problem worldwide, with trauma being a common
cause. PNI can lead to loss of sensory and motor functions, chronic neuropathic pain, and …

Genetic Identification and Characterisation of Novel Genes Implicated in Cerebellar Ataxia
Page 1 0 Genetic Identification and Characterisation of Novel Genes Implicated in Cerebellar …

Peroxisomal single enzyme and transporter deficiencies are inherited human diseases
caused by the absence of individual enzymatic activities exerted in peroxisomes. These …