The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal Transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

Role of oxidative damage in alzheimer's disease and neurodegeneration: From pathogenic mechanisms to biomarker discovery

FR Buccellato, M D'Anca, C Fenoglio, E Scarpini… - Antioxidants, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder accounting for over 50% of all
dementia patients and representing a leading cause of death worldwide for the global …

Combination of cell-penetrating peptides with nanomaterials for the potential therapeutics of central nervous system disorders: a review

Y Zhang, P Guo, Z Ma, P Lu, D Kebebe… - Journal of …, 2021 - Springer
Although nanomedicine have greatly developed and human life span has been extended,
we have witnessed the soared incidence of central nervous system (CNS) diseases …

Bioactive 2D nanomaterials for neural repair and regeneration

X He, Y Zhu, B Ma, X Xu, R Huang, L Cheng… - Advanced Drug Delivery …, 2022 - Elsevier
Biomaterials have provided promising strategies towards improving the functions of injured
tissues of the nervous system. Recently, 2D nanomaterials, such as graphene, layered …

Graphene-based nanomaterials in fighting the most challenging viruses and immunogenic disorders

M Ebrahimi, M Asadi, O Akhavan - ACS Biomaterials Science & …, 2021 - ACS Publications
Viral diseases have long been among the biggest challenges for healthcare systems around
the world. The recent Coronavirus Disease 2019 (COVID-19) pandemic is an example of …

Biomedical application of 2D nanomaterials in neuroscience

K Li, Q Ji, H Liang, Z Hua, X Hang, L Zeng… - Journal of …, 2023 - Springer
Abstract Two-dimensional (2D) nanomaterials, such as graphene, black phosphorus and
transition metal dichalcogenides, have attracted increasing attention in biology and …

[HTML][HTML] Spatiotemporal tracking of gold nanorods after intranasal administration for brain targeting

S Han, JTW Wang, E Yavuz, A Zam, N Rouatbi… - Journal of Controlled …, 2023 - Elsevier
Intranasal administration is becoming increasingly more attractive as a fast delivery route to
the brain for therapeutics circumventing the blood-brain barrier (BBB). Gold nanorods …

Nanomedicine and graphene-based materials: advanced technologies for potential treatments of diseases in the developing nervous system

G Cellot, A Franceschi Biagioni, L Ballerini - Pediatric Research, 2022 - nature.com
The interest in graphene-based nanomaterials (GBNs) application in nanomedicine, in
particular in neurology, steadily increased in the last decades. GBNs peculiar physical …

Graphene-and MXene-based materials for neuroscience: diagnostic and therapeutic applications

A Zarepour, Ç Karasu, Y Mir, MH Nematollahi… - Biomaterials …, 2023 - pubs.rsc.org
MXenes and graphene are two-dimensional materials that have gained increasing attention
in neuroscience, particularly in sensing, theranostics, and biomedical engineering. Various …

Advanced nanomaterials for modulating Alzheimer's related amyloid aggregation

X Shao, C Yan, C Wang, C Wang, Y Cao, Y Zhou… - Nanoscale …, 2023 - pubs.rsc.org
Alzheimer's disease (AD) is a common neurodegenerative disease that brings about
enormous economic pressure to families and society. Inhibiting abnormal aggregation of Aβ …