Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …

Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Galectins (formerly known as “S-type lectins”) are a subfamily of soluble proteins that
typically bind β-galactoside carbohydrates with high specificity. They are present in many …

Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

Over the past few decades, nanoengineered particles have gained increasing interest for
applications in the biomedical realm, including diagnosis, imaging, and therapy. When …

Cellular communication events are mediated by interactions between cell-surface sugars
and lectins, which are carbohydrate-binding proteins. Galectins are β-galactosyl-binding …

Introduction Galectins are ubiquitous in nature. They have established themselves as a
protein family of high therapeutic potential and play a role in a wide variety of diseases like …

Evasion of immune surveillance is an accepted hallmark of tumor progression. The
production of immune suppressive mediators by tumor cells is one of the major mechanisms …

A new series of orally available α-d-galactopyranosides with high affinity and specificity
toward galectin-1 have been discovered. High affinity and specificity were achieved by …

Among glycan-binding proteins, galectins, β-galactoside-binding lectins, exhibit relevant
biological roles and are implicated in many diseases, such as cancer and inflammation …