Simple Summary The genetic landscape of cutaneous T-cell lymphomas analyzed by
sequencing high throughput techniques shows a heterogeneous somatic mutational profile …

Simple Summary Autophagy is a dynamic and tightly regulated process that seems to have
dual effects in cancer. In some contexts, it can induce carcinogenesis and promote cancer …

Understanding the molecular mechanisms that contribute to the appearance of
chemotherapy resistant cell populations is necessary to improve cancer treatment. We have …

Current treatment options for autoimmune disease (AID) are essentially
immunosuppressive, inhibiting the inflammatory cascade, without curing the disease …

Background Transgender women (TW) are at increased risk for both human
immunodeficiency virus (HIV) and cardiovascular disease (CVD). Antiretroviral therapy …

Vaccines against SARS-CoV-2 are the most effective measure against the COVID-19
pandemic. The safety profile of mRNA vaccines in patients with rare diseases has not been …

Abstract The NOTCH-Delta-HES signaling cascade is regarded as a double-edged sword
owing to its dual tumor-suppressor and oncogenic roles, in different cellular environments. In …

Background: Indolent T cell lymphoproliferation of the gastrointestinal tract is a novel entity
recently added to the 2016 WHO classification of lymphoid neoplasms. Classically, these …

Gene therapy is a powerful biological tool that is reshaping therapeutic landscapes for
several diseases. Researchers are using both non-viral and viral-based gene therapy …

Understanding the molecular mechanisms that contribute to the appearance of
chemotherapy resistant cell populations is necessary to improve cancer treatment. We have …