Beta blockers are a recommended therapy in patients with heart failure with reduced
ejection fraction (HFrEF). Beta blockers markedly and unequivocally reduce mortality in …

心肌梗死后心脏重构涉及多种信号传导, 与心力衰竭, 心律失常密切相关. β 肾上腺素能受体(β-
AR) 参与凋亡, 炎症, 纤维化, 心肌肥大等病理过程, 在梗死后心脏重构中发挥关键的调节作用. 3 …

Context Carnitine has been associated with cardiac energy metabolism and heart failure,
but the association between its precursors—trimethyllysine (TML) and γ-butyrobetaine …

Methods: HF patients (n= 584) were recruited for the study. The patients were genotyped by
tetra-primer based allele specific polymerase chain reaction and confirmed with Sanger …

β2-Adrenoceptor (β2-AR) agonists are widely used as bronchodilators. The emerge of
ultralong acting β2-agonists is an important breakthrough in pulmonary medicine. In this …

Cancer progression involves complex interactions between tumor cells and the surrounding
microenvironment. Chronic psychosocial stress and sympathetic nervous system activation …

Aims Our objective was to investigate the association of common variants in the coding
region of advanced glycosylation end‐product specific receptor (RAGE) and the prognosis …

A variety of G protein-coupled receptors (GPCRs) are involved in the regulation of
cardiovascular function. The β-adrenoceptors (β-ARs), with three subtypes, are the dominant …

Precision medicine envisages the integration of an individual's clinical and biological
features obtained from laboratory tests, imaging, high-throughput omics and health records …

Migraine is considered one of the most disabling neurological disorder with a high
socioeconomic burden. Pharmacological management includes many classes of drugs …