Aims The prognosis of heart failure (HF) depends on genetic predisposition, and recent
studies have shown that impaired autophagy is involved in HF. This study was aimed to …

High-altitude pulmonary edema occurs most frequently in non-acclimatized low landers on
exposure to altitude≥ 2500 m. High-altitude pulmonary edema is a complex condition that …

Introduction: Dexmedetomidine (DXM) is widely used as an adjuvant to anesthesia or a
sedative medicine, and differences in individual sensitivity to the drug exist. This study …

During normal-and patho-physiological situations, the behavior of the beta2-adrenoreceptor
(β 2 AR) is influenced by polymorphic variants. The functional impact of such polymorphisms …

精准医学基于个体生物, 环境与生活方式暴露特征, 探索个体化的疾病预防与治疗策略.
常见慢性非传染性疾病大多是受遗传及环境因素共同影响的复杂疾病, 多数病因尚不完全清晰 …

Introducción: Los betabloqueantes (BBs) se utilizan como tratamiento de la isquemia en el
síndrome coronario agudo (SCA). En España, los más utilizados son bisoprolol y atenolol …

The purpose was to identify the Transient receptor potential (TRP) superfamily gene variants
associate with the prognosis of ischemic cardiomyopathy (ICM). A whole-exome sequencing …

Pharmacogenomics is the study of inherited genetic variation on drug pharmacokinetics and
pharmacodynamics to inform and personalise prescribing. There is a growing body of …

Purpose The aim of this study is to prospectively investigate the influence of ADRB and
COMT gene polymorphisms on postoperative outcomes of patients undergoing cardiac …

Purpose of review The rapidly evolving field of cardiovascular genetics has already
improved the care of patients with heart failure and families. The purpose of the current …