Multivariable prognostic model for heart failure in Chinese Han population‐based setting
M Huang, L Xiao, Y Sun, D Hu, Y Chen… - ESC Heart …, 2022 - Wiley Online Library
Aims The prognosis of heart failure (HF) depends on genetic predisposition, and recent
studies have shown that impaired autophagy is involved in HF. This study was aimed to …
studies have shown that impaired autophagy is involved in HF. This study was aimed to …
Vascular homeostasis at high-altitude: role of genetic variants and transcription factors
N Chanana, T Palmo, JH Newman… - Pulmonary …, 2020 - journals.sagepub.com
High-altitude pulmonary edema occurs most frequently in non-acclimatized low landers on
exposure to altitude≥ 2500 m. High-altitude pulmonary edema is a complex condition that …
exposure to altitude≥ 2500 m. High-altitude pulmonary edema is a complex condition that …
Genetic polymorphisms are associated with individual susceptibility to dexmedetomidine
Y Ding, A Liu, Y Wang, S Zhao, S Huang, H Zhu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Dexmedetomidine (DXM) is widely used as an adjuvant to anesthesia or a
sedative medicine, and differences in individual sensitivity to the drug exist. This study …
sedative medicine, and differences in individual sensitivity to the drug exist. This study …
[HTML][HTML] CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of β2AR in isogenic hPSC-derived cardiomyocytes
A Kondrashov, NANM Yusof, A Hasan… - … Therapy Methods & …, 2021 - cell.com
During normal-and patho-physiological situations, the behavior of the beta2-adrenoreceptor
(β 2 AR) is influenced by polymorphic variants. The functional impact of such polymorphisms …
(β 2 AR) is influenced by polymorphic variants. The functional impact of such polymorphisms …
[HTML][HTML] 人群研究在慢性非传染性疾病精准医学中的应用
吴涛, 王斯悦 - 2021 - aammt.tmmu.edu.cn
精准医学基于个体生物, 环境与生活方式暴露特征, 探索个体化的疾病预防与治疗策略.
常见慢性非传染性疾病大多是受遗传及环境因素共同影响的复杂疾病, 多数病因尚不完全清晰 …
常见慢性非传染性疾病大多是受遗传及环境因素共同影响的复杂疾病, 多数病因尚不完全清晰 …
Análisis de variantes genéticas asociadas a la respuesta a bisoprolol en pacientes con síndrome coronario agudo sometidos a intervención coronaria percutánea con …
C Castaño-Amores - 2024 - digibug.ugr.es
Introducción: Los betabloqueantes (BBs) se utilizan como tratamiento de la isquemia en el
síndrome coronario agudo (SCA). En España, los más utilizados son bisoprolol y atenolol …
síndrome coronario agudo (SCA). En España, los más utilizados son bisoprolol y atenolol …
A TRPV1 common missense variant affected the prognosis of ischemic cardiomyopathy
S Li, L Xiao, Y Sun, S Hu, D Hu - Medicine, 2022 - journals.lww.com
The purpose was to identify the Transient receptor potential (TRP) superfamily gene variants
associate with the prognosis of ischemic cardiomyopathy (ICM). A whole-exome sequencing …
associate with the prognosis of ischemic cardiomyopathy (ICM). A whole-exome sequencing …
Cardiovascular pharmacogenomics–Molecular basis of protective and adverse drug response
C du Toit, M Kassi, S Padmanabhan - Genomic and Molecular …, 2024 - Elsevier
Pharmacogenomics is the study of inherited genetic variation on drug pharmacokinetics and
pharmacodynamics to inform and personalise prescribing. There is a growing body of …
pharmacodynamics to inform and personalise prescribing. There is a growing body of …
Influence of ADRB1, ADRB2, and COMT genetic polymorphisms on postoperative outcomes of patients undergoing cardiac valve surgery
S Dai, W Ma, G Qin, L Wang, E Wang - Clinical Therapeutics, 2021 - Elsevier
Purpose The aim of this study is to prospectively investigate the influence of ADRB and
COMT gene polymorphisms on postoperative outcomes of patients undergoing cardiac …
COMT gene polymorphisms on postoperative outcomes of patients undergoing cardiac …
Updates on the genetic paradigm in heart failure
AN Rosenbaum, N Pereira - Current Treatment Options in Cardiovascular …, 2019 - Springer
Purpose of review The rapidly evolving field of cardiovascular genetics has already
improved the care of patients with heart failure and families. The purpose of the current …
improved the care of patients with heart failure and families. The purpose of the current …