Relation Between the Dantu Blood Group Variant and Bacteremia in Kenyan Children: A Population-Based Case-Control Study
SN Kariuki, JJ Gilchrist, S Uyoga… - The Journal of …, 2024 - academic.oup.com
Abstract Background The Dantu blood group variant protects against Plasmodium
falciparum infections, but its wider consequences have not been previously explored. Here …
falciparum infections, but its wider consequences have not been previously explored. Here …
Biophysical tools and concepts enable understanding of asexual blood stage malaria
Forces and mechanical properties of cells and tissues set constraints on biological functions,
and are key determinants of human physiology. Changes in cell mechanics may arise from …
and are key determinants of human physiology. Changes in cell mechanics may arise from …
Novel stem cell technologies are powerful tools to understand the impact of human factors on Plasmodium falciparum malaria
Plasmodium falciparum parasites have a complex life cycle, but the most clinically relevant
stage of the disease is the invasion of erythrocytes and the proliferation of the parasite in the …
stage of the disease is the invasion of erythrocytes and the proliferation of the parasite in the …
Two prevalent∼ 100-kb GYPB deletions causative of the GPB-Deficient blood group MNS phenotype S–s–U–in black Africans
C Gassner, GA Denomme, C Portmann… - Transfusion Medicine …, 2020 - karger.com
The U antigen (MNS5) is one of 49 antigens belonging to the MNS blood group system
(ISBT002) carried on glycophorins A (GPA) and B (GPB). U is present on the red blood cells …
(ISBT002) carried on glycophorins A (GPA) and B (GPB). U is present on the red blood cells …
From Genome-wide Association Studies to Functional Variants: ARL14 Cis-regulatory Variants Are Associated With Severe Malaria
M Adjemout, F Gallardo, M Torres… - The Journal of …, 2024 - academic.oup.com
Background Genome-wide association studies have identified several nonfunctional tag
single-nucleotide polymorphisms (SNPs) associated with severe malaria. We hypothesized …
single-nucleotide polymorphisms (SNPs) associated with severe malaria. We hypothesized …
Limited genetic variations of the Rh5-CyRPA-Ripr invasion complex in Plasmodium falciparum parasite population in selected malaria-endemic regions, Kenya
The invasion of human erythrocytes by Plasmodium falciparum merozoites requires
interaction between parasite ligands and host receptors. Interaction of Pf Rh5-CyRPA-Ripr …
interaction between parasite ligands and host receptors. Interaction of Pf Rh5-CyRPA-Ripr …
Risk score prediction model based on single nucleotide polymorphism for predicting malaria: a machine learning approach
KY Tai, J Dhaliwal, KS Wong - BMC bioinformatics, 2022 - Springer
Background The malaria risk prediction is currently limited to using advanced statistical
methods, such as time series and cluster analysis on epidemiological data. Nevertheless …
methods, such as time series and cluster analysis on epidemiological data. Nevertheless …
Genetic variations in human ATP2B4 gene alter Plasmodium falciparum in vitro growth in RBCs from Gambian adults
Abstract Background Polymorphisms in ATP2B4 coding for PMCA4b, the primary regulator
of erythrocyte calcium concentration, have been shown by GWAS and cross-sectional …
of erythrocyte calcium concentration, have been shown by GWAS and cross-sectional …
[HTML][HTML] A Whole-Genome Scan Revealed Genomic Features and Selection Footprints of Mengshan Cattle
H Cheng, Y Lyu, Z Liu, C Li, K Qu, S Li, Z Ahmed, W Ma… - Genes, 2024 - mdpi.com
(1) Background: Mengshan cattle from the Yimeng mountainous region in China stand out
as a unique genetic resource, known for their adaptive traits and environmental resilience …
as a unique genetic resource, known for their adaptive traits and environmental resilience …
The effects of dyslipidaemia and cholesterol modulation on erythrocyte susceptibility to malaria parasite infection
Background Malaria disease commences when blood-stage parasites, called merozoites,
invade human erythrocytes. Whilst the process of invasion is traditionally seen as being …
invade human erythrocytes. Whilst the process of invasion is traditionally seen as being …