Oxidative stress is significantly involved in the pathogenesis and progression of chronic
obstructive pulmonary disease (COPD). Combining antioxidant drugs or nutrients results in …

Although dry powder inhalers (DPIs) have attracted great interest compared to nebulizers
and metered-dose inhalers (MDIs), drug deposition in the deep lung is still insufficient to …

Respiratory antibiotics delivery has been appreciated for its high local concentration at the
infection sites. Certain formulation strategies are required to improve pulmonary drug …

As inhaler design is rarely studied but critically important in pulmonary drug delivery, this
study investigated the influence of inhaler designs, including a novel spiral channel …

Lower respiratory infections are the third leading cause of death, as stated by the world
health organization. The pulmonary route requires reduced dose, exhibits immediate drug …

Chronic obstructive pulmonary disease (COPD) refers to a collection of ailments that are
responsible for blockage of airflow and breathing problems like chronic bronchitis and …

Chronic obstructive pulmonary disease has been the most widespread worldwide health
problem that has influenced millions of people worldwide. The freeze-dried inhalable …

Abstract Quality by Design (QbD) is a methodical approach to pharmaceutical product
development that begins with predefined objectives and emphasizes product and process …

The pulmonary drug delivery systems (PDDSs) are considered complex systems because of
having many variables related to formulations, processes, and devices. In general terms, a …

The purpose of the present study was to formulate and evaluate microemulsion based in situ
gel of Acyclovir (ACV) for the vaginal delivery. The solubility of ACV in oils and surfactants …