Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution

X Su, KD Lane, L Xia, JM Sá… - Clinical microbiology …, 2019 - Am Soc Microbiol
Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

[HTML][HTML] Plasmodium vivax vaccine: What is the best way to go?

GTS Veiga, MR Moriggi, JF Vettorazzi… - Frontiers in …, 2023 - frontiersin.org
Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

Growing evidence of Plasmodium vivax across malaria-endemic Africa

KA Twohig, DA Pfeffer, JK Baird, RN Price… - PLoS neglected …, 2019 - journals.plos.org
Effective malaria control strategies require an accurate understanding of the epidemiology of
locally transmitted Plasmodium species. Compared to Plasmodium falciparum infection …

Bone marrow is a major parasite reservoir in Plasmodium vivax infection

N Obaldia III, E Meibalan, JM Sa, S Ma, MA Clark… - MBio, 2018 - Am Soc Microbiol
Plasmodium vivax causes heavy burdens of disease across malarious regions worldwide.
Mature P. vivax asexual and transmissive gametocyte stages occur in the blood circulation …

Duffy antigen is expressed during erythropoiesis in Duffy-negative individuals

C Dechavanne, S Dechavanne, J Bosch, S Metral… - Cell Host & Microbe, 2023 - cell.com
The erythrocyte silent Duffy blood group phenotype in Africans is thought to confer
resistance to Plasmodium vivax blood-stage infection. However, recent studies report P …

Malaria vaccine candidate based on Duffy-binding protein elicits strain transcending functional antibodies in a Phase I trial

K Singh, P Mukherjee, AR Shakri, A Singh, G Pandey… - NPJ vaccines, 2018 - nature.com
Reticulocyte invasion by Plasmodium vivax requires interaction of the Duffy-binding protein
(PvDBP) with host Duffy antigen receptor for chemokines (DARCs). The binding domain of …

Systems biology of malaria explored with nonhuman primates

MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites

DE Loy, LJ Plenderleith… - Proceedings of the …, 2018 - National Acad Sciences
Wild-living African apes are endemically infected with parasites that are closely related to
human Plasmodium vivax, a leading cause of malaria outside Africa. This finding suggests …

Potential hidden Plasmodium vivax malaria reservoirs from low parasitemia Duffy-negative Ethiopians: Molecular evidence

A Abebe, I Bouyssou, S Mabilotte… - PLoS neglected …, 2023 - journals.plos.org
Background The interaction between the Plasmodium vivax Duffy-binding protein and the
corresponding Duffy Antigen Receptor for Chemokines (DARC) is primarily responsible for …

[HTML][HTML] The global burden of Plasmodium vivax malaria is obscure and insidious

KE Battle, JK Baird - PLoS Medicine, 2021 - journals.plos.org
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