[HTML][HTML] Brugada syndrome: diagnosis, risk stratification and management

JB Gourraud, J Barc, A Thollet, H Le Marec… - Archives of …, 2017 - Elsevier
Brugada syndrome is a rare inherited arrhythmia syndrome leading to an increased risk of
sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific …

[HTML][HTML] The link between sex hormones and susceptibility to cardiac arrhythmias: from molecular basis to clinical implications

S Costa, AM Saguner, A Gasperetti, D Akdis… - Frontiers in …, 2021 - frontiersin.org
It is well-known that gender is an independent risk factor for some types of cardiac
arrhythmias. For example, males have a greater prevalence of atrial fibrillation and the …

[HTML][HTML] Brugada syndrome: A comprehensive review of pathophysiological mechanisms and risk stratification strategies

KHC Li, S Lee, C Yin, T Liu, T Ngarmukos, G Conte… - IJC Heart & …, 2020 - Elsevier
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to
ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly …

Brugada syndrome: oligogenic or mendelian disease?

MM Monasky, E Micaglio, G Ciconte… - International Journal of …, 2020 - mdpi.com
Brugada syndrome (BrS) is diagnosed by a coved-type ST-segment elevation in the right
precordial leads on the electrocardiogram (ECG), and it is associated with an increased risk …

Brugada syndrome: From molecular mechanisms and genetics to risk stratification

IP Popa, DN Șerban, MA Mărănducă… - International Journal of …, 2023 - mdpi.com
Brugada syndrome (BrS) is a rare hereditary arrhythmia disorder, with a distinctive ECG
pattern, correlated with an increased risk of ventricular arrhythmias and sudden cardiac …

Sudden death in the young: information for the primary care provider

CC Erickson, JC Salerno, S Berger, R Campbell… - …, 2021 - publications.aap.org
There are multiple conditions that can make children prone to having a sudden cardiac
arrest (SCA) or sudden cardiac death (SCD). Efforts have been made by multiple …

Brugada syndrome: A general cardiologist's perspective

MM Polovina, M Vukicevic, B Banko, GYH Lip… - European Journal of …, 2017 - Elsevier
Brugada syndrome (BrS) is one of the commonest inherited primary arrhythmia syndromes
typically presenting with arrhythmic syncope or sudden cardiac death (SCD) due to …

Unmasking the molecular link between arrhythmogenic cardiomyopathy and Brugada syndrome

J Moncayo-Arlandi, R Brugada - Nature Reviews Cardiology, 2017 - nature.com
The intercalated discs that connect cardiomyocytes control cell-to-cell adhesion and
communication. Several macromolecular structures (desmosomes, fascia adherens …

Understanding mutational effects in digenic diseases

A Gazzo, D Raimondi, D Daneels… - Nucleic acids …, 2017 - academic.oup.com
To further our understanding of the complexity and genetic heterogeneity of rare diseases, it
has become essential to shed light on how combinations of variants in different genes are …

[HTML][HTML] Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient

E Selga, F Sendfeld, R Martinez-Moreno… - Journal of molecular and …, 2018 - Elsevier
Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion
channel function, yet our understanding of the underlying cellular mechanisms is …