570 Circ Cardiovasc Genet December 2016 potassium channel dysfunction has also been
proposed recently as a possible mechanism for some stillbirths given that LQTS …

Background Although the implantable cardioverter–defibrillator (ICD) remains the main
therapy for Brugada syndrome (BrS), it does not reduce life-threatening ventricular …

Brugada syndrome (BrS), is a primary electrical disorder predisposing affected individuals to
sudden cardiac death via the development of ventricular tachycardia and fibrillation (VT/VF) …

Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion
channel function, yet our understanding of the underlying cellular mechanisms is …

Abstract Aims The Brugada syndrome (BrS) is an inherited cardiac disorder predisposing to
ventricular arrhythmias. Despite considerable efforts, its genetic basis and cellular …

Next generation sequencing (NGS) has revolutionised rare disease diagnostics.
Concomitant with advancing technologies has been a rise in the number of new gene …

There are significant differences in clinical presentation and treatment of atrial fibrillation
(AF) between women and men. The primary goal of AF management is to restore sinus …

Background: After sudden cardiac death with negative autopsy, clinical screening of
relatives identifies a high proportion of inherited arrhythmia syndrome. However, the efficacy …

Rauwolfia serpentina is reported in an Ayurvedic medicinal system for centuries, for the
treatment of various ailments such as snakebites, insomnia, hypertension, and insanity …

Hundreds of thousands of people die each year as a result of sudden cardiac death, and
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …