New insights into the genetic basis of inherited arrhythmia syndromes
570 Circ Cardiovasc Genet December 2016 potassium channel dysfunction has also been
proposed recently as a possible mechanism for some stillbirths given that LQTS …
proposed recently as a possible mechanism for some stillbirths given that LQTS …
The QUIDAM study: hydroquinidine therapy for the management of Brugada syndrome patients at high arrhythmic risk
A Andorin, JB Gourraud, J Mansourati, S Fouchard… - Heart Rhythm, 2017 - Elsevier
Background Although the implantable cardioverter–defibrillator (ICD) remains the main
therapy for Brugada syndrome (BrS), it does not reduce life-threatening ventricular …
therapy for Brugada syndrome (BrS), it does not reduce life-threatening ventricular …
Electrophysiological mechanisms of Brugada syndrome: insights from pre-clinical and clinical studies
G Tse, T Liu, KHC Li, V Laxton, YWF Chan… - Frontiers in …, 2016 - frontiersin.org
Brugada syndrome (BrS), is a primary electrical disorder predisposing affected individuals to
sudden cardiac death via the development of ventricular tachycardia and fibrillation (VT/VF) …
sudden cardiac death via the development of ventricular tachycardia and fibrillation (VT/VF) …
[HTML][HTML] Sodium channel current loss of function in induced pluripotent stem cell-derived cardiomyocytes from a Brugada syndrome patient
E Selga, F Sendfeld, R Martinez-Moreno… - Journal of molecular and …, 2018 - Elsevier
Brugada syndrome predisposes to sudden death due to disruption of normal cardiac ion
channel function, yet our understanding of the underlying cellular mechanisms is …
channel function, yet our understanding of the underlying cellular mechanisms is …
RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome
Abstract Aims The Brugada syndrome (BrS) is an inherited cardiac disorder predisposing to
ventricular arrhythmias. Despite considerable efforts, its genetic basis and cellular …
ventricular arrhythmias. Despite considerable efforts, its genetic basis and cellular …
Challenges in the diagnosis and discovery of rare genetic disorders using contemporary sequencing technologies
Next generation sequencing (NGS) has revolutionised rare disease diagnostics.
Concomitant with advancing technologies has been a rise in the number of new gene …
Concomitant with advancing technologies has been a rise in the number of new gene …
Gender differences in arrhythmias: focused on atrial fibrillation
XT Tian, YJ Xu, YQ Yang - Journal of Cardiovascular Translational …, 2020 - Springer
There are significant differences in clinical presentation and treatment of atrial fibrillation
(AF) between women and men. The primary goal of AF management is to restore sinus …
(AF) between women and men. The primary goal of AF management is to restore sinus …
Clinical yield of familial screening after sudden death in young subjects: the French experience
P Quenin, F Kyndt, P Mabo, J Mansourati… - Circulation …, 2017 - Am Heart Assoc
Background: After sudden cardiac death with negative autopsy, clinical screening of
relatives identifies a high proportion of inherited arrhythmia syndrome. However, the efficacy …
relatives identifies a high proportion of inherited arrhythmia syndrome. However, the efficacy …
Evaluating the therapeutic efficiency and drug targeting ability of alkaloids present in Rauwolfia serpentina
M Singh - International Journal of Green Pharmacy (IJGP), 2017 - brncop.org
Rauwolfia serpentina is reported in an Ayurvedic medicinal system for centuries, for the
treatment of various ailments such as snakebites, insomnia, hypertension, and insanity …
treatment of various ailments such as snakebites, insomnia, hypertension, and insanity …
Noncoding RNAs and Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Cardiac Arrhythmic Brugada Syndrome
B Theisen, A Holtz, V Rajagopalan - Cells, 2023 - mdpi.com
Hundreds of thousands of people die each year as a result of sudden cardiac death, and
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …