Background The aim of this study is to report on the genetic composition of Brugada
syndrome (BrS) patients undergoing genetic testing in Hong Kong. Methods Patients with …

Aims Several inherited arrhythmic diseases have been linked to single gene mutations in
cardiac ion channels and interacting proteins. However, the mechanisms underlying most …

Background: Brugada syndrome (BrS) is an inherited primary channelopathy syndrome
associated to sudden cardiac death. Overall, variants have been identified in eighteen …

Abstract Long QT syndrome (LQTS), Brugada syndrome (BrS), and catecholaminergic
polymorphic ventricular tachycardia (CPVT) are genetic diseases of the heart caused by …

Rhythm disturbances are life-threatening cardiovascular diseases, accounting for many
deaths annually worldwide. Abnormal electrical activity might arise in a structurally normal …

Abstract Background Brugada syndrome (BrS) is an inherited cardiac arrhythmogenic
disease that predisposes patients to sudden cardiac death. It is associated with mutations in …

Background: Brugada syndrome (BrS) is a rare cardiac arrhythmia characterized by sudden
death associated with electrocardiogram patterns characterized by incomplete right bundle …

Point mutations are the most common cause of inherited diseases. Bioinformatics tools can
help to predict the pathogenicity of mutations found during genetic screening, but they may …

Brugada syndrome (BrS) is a complex genetic cardiac ion channel disease that causes a
high predisposition to sudden cardiac death. Considering that its heterogeneity in clinical …

Brugada syndrome (BrS) is an inherited arrhythmia syndrome characterized by right bundle
branch block and dynamic ST-segment changes in precordial leads V1–V3. In patients with …