Near‐infrared‐II quantum dots for in vivo imaging and cancer therapy

LL Chen, L Zhao, ZG Wang, SL Liu, DW Pang - Small, 2022 - Wiley Online Library
In vivo fluorescence imaging can perform real‐time, noninvasive, and high spatiotemporal
resolution imaging to accurately obtain the dynamic biological information in vivo, which …

Interactions between nanoparticles and lymphatic systems: Mechanisms and applications in drug delivery

Y Tang, B Liu, Y Zhang, Y Liu, Y Huang… - Advanced Drug Delivery …, 2024 - Elsevier
The lymphatic system has garnered significant attention in drug delivery research due to the
advantages it offers, such as enhancing systemic exposure and enabling lymph node …

Targeting nanoparticles to malignant tumors

N Sharma, K Bietar, U Stochaj - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Nanomaterials are at the forefront of health research and development. Among different
nanomaterials, nanoparticles are especially promising for cancer theranostics. However …

[HTML][HTML] Potential applications of using tissue-specific EVs in targeted therapy and vaccinology

TP Lehmann, M Golik, J Olejnik, M Łukaszewska… - Biomedicine & …, 2023 - Elsevier
Many cell types secrete spherical membrane bodies classified as extracellular vesicles
(EVs). EVs participate in intercellular communication and are present in body fluids …

Non-invasive molecular imaging for precision diagnosis of metastatic lymph nodes: opportunities from preclinical to clinical applications

Z Cheng, J Ma, L Yin, L Yu, Z Yuan, B Zhang… - European Journal of …, 2023 - Springer
Lymph node metastasis is an indicator of the invasiveness and aggressiveness of cancer. It
is a vital prognostic factor in clinical staging of the disease and therapeutic decision-making …

NIR-II Fluorescence Imaging for the Detection and Resection of Cancerous Foci and Lymph Nodes in Early-Stage Orthotopic and Advanced-Stage Metastatic Ovarian …

T Pu, Y Liu, Y Pei, J Peng, Z Wang, M Du… - … Applied Materials & …, 2023 - ACS Publications
The high mortality rate of ovarian cancer can be primarily attributed to late diagnosis and
early lymph node (LN) metastasis. The anatomically deep-located ovaries own intricate …

Lymphatic targeting for therapeutic application using nanoparticulate systems

N Singh, M Handa, V Singh, P Kesharwani… - Journal of Drug …, 2022 - Taylor & Francis
The lymphatic system has grasped attention of researchers to a greater extent. The
conventional methods of lymphatic delivery are now being modified to include …

[HTML][HTML] Extracellular vesicles and melanoma: New perspectives on tumor microenvironment and metastasis

A Benito-Martín, MG Jasiulionis… - Frontiers in Cell and …, 2023 - frontiersin.org
Secreted extracellular vesicles (EVs) are lipid bilayer particles without functional nucleus
naturally released from cells which constitute an intercellular communication system. There …

Hybrid lymphatic drug delivery vehicles as a new avenue for targeted therapy: Lymphatic trafficking, applications, challenges, and future horizons

GI Harisa, AY Sherif, FK Alanazi - The Journal of Membrane Biology, 2023 - Springer
Lymphatic drug targeting is an effective approach for targeting immunomodulators, and
chemotherapeutic drugs at a specific organ or cellular location. The cellular, paracellular …

Multifunctional nanosystems with enhanced cellular uptake for tumor therapy

Z Ma, MF Foda, Y Zhao, H Han - Advanced Healthcare …, 2022 - Wiley Online Library
Rapid development of nanotechnology provides promising strategies in biomedicine,
especially in tumor therapy. In particular, the cellular uptake of nanosystems is not only a …