A review of cardiovascular effects and underlying mechanisms of legacy and emerging per-and polyfluoroalkyl substances (PFAS)

ZJ Wen, YJ Wei, YF Zhang, YF Zhang - Archives of Toxicology, 2023 - Springer
Cardiovascular disease (CVD) poses the leading threats to human health and life, and their
occurrence and severity are associated with exposure to environmental pollutants. Per-and …

[HTML][HTML] Associations of per-and polyfluoroalkyl substances (PFAS) and their mixture with oxidative stress biomarkers during pregnancy

KR Taibl, S Schantz, MT Aung, A Padula… - Environment …, 2022 - Elsevier
Background Oxidative stress from excess reactive oxygen species (ROS) is a hypothesized
contributor to preterm birth. Per-and polyfluoroalkyl substances (PFAS) exposure is reported …

Perfluorohexanesulfonic acid (PFHxS) induces oxidative stress and causes developmental toxicities in zebrafish embryos

ZS Ulhaq, WKF Tse - Journal of Hazardous Materials, 2023 - Elsevier
Perfluorohexanesulfonic acid (PFHxS) is a short-chain perfluoroalkyl substance widely used
to replace the banned perfluorooctanesulfonic acid (PFOS) in different industrial and …

PFAS-induced lipidomic dysregulations and their associations with developmental toxicity in zebrafish embryos

Z Yang, L Fu, M Cao, F Li, J Li, Z Chen, A Guo… - Science of the Total …, 2023 - Elsevier
Per-and polyfluoroalkyl substances (PFASs) are persistent environmental contaminants,
posing developmental toxicity to fish and human. PFAS-induced lipid metabolism disorders …

Integrative multi-omics reveals analogous developmental neurotoxicity mechanisms between perfluorobutanesulfonic acid and perfluorooctanesulfonic acid in …

EK Min, H Lee, EJ Sung, SW Seo, M Song… - Journal of Hazardous …, 2023 - Elsevier
The molecular mechanism of perfluorobutanesulfonic acid (PFBS), an alternative to legacy
perfluorooctanesulfonic acid (PFOS), is not fully understood yet. Therefore, we conducted a …

[HTML][HTML] Zebra-Sphinx: modeling sphingolipidoses in zebrafish

L Mignani, J Guerra, M Corli, D Capoferri… - International Journal of …, 2023 - mdpi.com
Sphingolipidoses are inborn errors of metabolism due to the pathogenic mutation of genes
that encode for lysosomal enzymes, transporters, or enzyme cofactors that participate in the …

Plasma concentrations of per-and polyfluoroalkyl substances are associated with perturbations in lipid and amino acid metabolism

N Prince, S Begum, L Mínguez-Alarcón… - Chemosphere, 2023 - Elsevier
Exposure to per-and polyfluoroalkyl substances (PFAS) through the environment can lead to
harmful health outcomes and the development of disease. However, little is known about …

[HTML][HTML] PFHxS exposure and the risk of non-alcoholic fatty liver disease

ZS Ulhaq, WKF Tse - Genes, 2024 - mdpi.com
Perfluorohexanesulfonic acid (PFHxS) is a highly prevalent environmental pollutant, often
considered to be less toxic than other poly-and perfluoroalkyl substances (PFASs). Despite …

Integrated Analysis of Per-and Polyfluoroalkyl Substance Exposure and Metabolic Profiling of Elderly Residents Living near Industrial Plants

Y Yang, X Wang, M Yang, S Wei… - Environmental Science & …, 2024 - ACS Publications
Per-and polyfluoroalkyl substances (PFASs) are widely used in industrial production,
causing potential health risks to the residents living around chemical industrial plants; …

[HTML][HTML] A comprehensive untargeted metabolomics study in zebrafish embryos exposed to perfluorohexane sulfonate (PFHxS)

M Xu, J Legradi, P Leonards - Science of The Total Environment, 2023 - Elsevier
Perfluorohexane sulfonate (PFHxS) is one of the short-chain perfluoroalkyl substances
(PFASs), and frequently detected in the environment, humans, and wildlife, but a detailed …