Female subfertility

CM Farquhar, S Bhattacharya, S Repping… - Nature reviews Disease …, 2019 - nature.com
Subfertility is common and affects one in six couples, half of whom lack an explanation for
their delay in conceiving. Developments in the diagnosis and treatment of subfertility over …

[HTML][HTML] Why are multiple pregnancy rates and single embryo transfer rates so different globally, and what do we do about it?

GD Adamson, RJ Norman - Fertility and Sterility, 2020 - Elsevier
In the early years of in vitro fertilization, overall pregnancy rates were low, and it was
considered necessary to transfer more than one embryo to increase the chances of …

Observational retrospective study of UK national success, risks and costs for 319,105 IVF/ICSI and 30,669 IUI treatment cycles

G Bahadur, R Homburg, JE Bosmans, JAF Huirne… - BMJ open, 2020 - bmjopen.bmj.com
Objective To compare success rates, associated risks and cost-effectiveness between
intrauterine insemination (IUI) and in vitro fertilisation (IVF). Design Retrospective …

[HTML][HTML] The crafting of hope: contextualising add-ons in the treatment trajectories of IVF patients

M Perrotta, J Hamper - Social Science & Medicine, 2021 - Elsevier
The proliferation and popularity of additional treatments in IVF, also known as add-ons, has
generated widespread discussion and controversy in the UK, where concerns have …

IVF add‐ons in Australia and New Zealand: A systematic assessment of IVF clinic websites

S Lensen, S Chen, L Goodman… - Australian and New …, 2021 - Wiley Online Library
Background In vitro fertilisation (IVF)'add‐ons' are extra (non‐essential) procedures,
techniques or medicines, which usually claim to increase the chance of a successful IVF …

[HTML][HTML] In vitro fertilization add-ons for the endometrium: it doesn't add-up

S Lensen, N Shreeve, KT Barnhart, A Gibreel, EHY Ng… - Fertility and sterility, 2019 - Elsevier
The probability of live birth from an in vitro fertilization (IVF) cycle is modest. Many additional
treatments (add-ons) are available which promise to improve the success of IVF. This review …

Repeated implantation failure (RIF): an iatrogenic meaningless definition that generates unnecessary and costly use of add-on procedures

Z Ben Rafael - Human Reproduction, 2020 - academic.oup.com
This opinion paper addresses the literature regarding repeated implantation failure (RIF) in
IVF embryo transfer programmes. We provide several lines of discussion as to why such …

[HTML][HTML] The trouble with IVF and randomised control trials: Professional legitimation narratives on time-lapse imaging and evidence-informed care

M Perrotta, A Geampana - Social Science & Medicine, 2020 - Elsevier
Focusing on the case of time-lapse imaging (TLI), this paper analyses how medical
professionals negotiate the use of new 'add-on'fertility treatments in light of the limited …

Ethical development of stem-cell-based interventions

A MacPherson, J Kimmelman - Nature Medicine, 2019 - nature.com
The process of developing new and complex stem-cell-based therapeutics is incremental
and requires decades of sustained collaboration among different stakeholders. In this …

Enacting evidence‐based medicine in fertility care: Tensions between commercialisation and knowledge standardisation

M Perrotta, A Geampana - Sociology of Health & Illness, 2021 - Wiley Online Library
In this article we explore the recent enactment of evidence‐based medicine (EBM) in the
field of fertility care. We aim to contribute to the medical sociology literature through an …