[HTML][HTML] The Impact of BRAF V600E Mutation Allele Frequency on the Histopathological Characteristics of Thyroid Cancer

M Abdulhaleem, S Bandargal, MP Pusztaszeri… - Cancers, 2023 - mdpi.com
Simple Summary This study aimed to investigate the relationship between the allele
frequency (AF) of the BRAF V600E mutation and the histopathological features of papillary …

[HTML][HTML] STRA6 regulates tumor immune microenvironment and is a prognostic marker in BRAF-mutant papillary thyroid carcinoma

W He, Y Sun, J Ge, X Wang, B Lin, S Yu, Y Li… - Frontiers in …, 2023 - frontiersin.org
Background BRAF mutation is one of the most common genetic alterations contributing to
the initiation and progression of papillary thyroid carcinoma (PTC). However, the prognostic …

[HTML][HTML] Mutational profiling of Chinese patients with thyroid cancer

Y Du, S Zhang, G Zhang, J Hu, L Zhao… - Frontiers in …, 2023 - frontiersin.org
Background The incidence of thyroid cancer in China has rapidly increased in recent
decades. As the genetic profiles of thyroid cancer vary dramatically between different …

Radioactive iodine-refractory pulmonary metastases of papillary thyroid cancer in children, adolescents, and young adults

T Tian, S Huang, H Dai, M Qi, B Liu… - The Journal of Clinical …, 2023 - academic.oup.com
Context Few studies have explored radioactive iodine–refractory (RAIR) disease in children,
adolescents, and young adults with papillary thyroid cancer (CAYA-PTC). Objective This …

Clinicopathological Features of CCDC6-RET and NCOA4-RET Fusions in Thyroid Cancer: A Single-center Retrospective Cohort Study in a Chinese Population

Z Wang, Q Yao, L Bao, H Chang, M Ren, T Xue, R Wei… - Thyroid, 2024 - liebertpub.com
Background: The rearranged during transfection (RET) proto-oncogene fusion is common in
papillary thyroid cancer (PTC), varying across ethnic groups. However, comprehensive …

Landscape of gene mutation in Chinese thyroid cancer patients: Construction and validation of lymph node metastasis prediction model based on clinical features and …

M Wei, R Wang, W Zhang, J Zhang, Q Fang… - Cancer …, 2023 - Wiley Online Library
Objectives Reporting the clinicopathological information of thyroid cancer (TC) patients from
a central medical center of east China, and constructing the nomogram predicting lymph …

[HTML][HTML] Papillary Thyroid Carcinoma: Correlation Between Molecular and Clinical Features

Q Wang, B Yu, S Zhang, D Wang, Z Xiao… - Molecular Diagnosis & …, 2024 - Springer
Background Thyroid cancer is prevalent worldwide, including in China, where its incidence
is on the rise. Papillary thyroid carcinoma (PTC) is the predominant subtype. Investigating …

[HTML][HTML] Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a …

J Huang, J Wang, J Xv, J Wang, G Wang… - Clinical and Experimental …, 2024 - Springer
The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in
papillary thyroid carcinoma (PTC) remains controversial. We aimed to investigate the AF of …

[PDF][PDF] 临床甲状腺癌基因检测报告解读的现状与思考

彭颖, 程若川 - 中国普通外科杂志, 2023 - zpwz.net
摘要基因测序是实现肿瘤精准医疗的基础手段, 可辅助肿瘤诊断, 判断患者预后,
指导靶向药物治疗等. 近年来, 基因测序技术已广泛应用于甲状腺癌的临床诊治工作中 …

[HTML][HTML] Selpercatinib: A narrative drug review

PE Raj, R Bhaskar, S Anne - Cancer Research, Statistics, and …, 2024 - journals.lww.com
Rearranged during transfection (RET) alteration promotes oncogenesis in a few cancers.
RET mutation positivity is seen in approximately 70% of medullary thyroid cancers, around …