The promising potential of reverse vaccinology-based next-generation vaccine development over conventional vaccines against antibiotic-resistant bacteria
The clinical use of antibiotics has led to the emergence of multidrug-resistant (MDR)
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …
bacteria, leading to the current antibiotic resistance crisis. To address this issue, next …
[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics
DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …
study the immune system. Recently, the principles of reverse vaccinology have united with …
Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe
public health complications in humans. There are currently no licensed treatments or …
public health complications in humans. There are currently no licensed treatments or …
Immunoinformatics-guided designing of epitope-based subunit vaccine from Pilus assembly protein of Acinetobacter baumannii bacteria
Acinetobacter baumannii, a prominent pathogen responsible for chronic infections in the
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …
blood, urinary tract, and lungs, has a high mortality due to its virulence and limited …
Designing of multi-epitope peptide vaccine against Acinetobacter baumannii through combined immunoinformatics and protein interaction–based approaches
J Dey, SR Mahapatra, PK Singh… - Immunologic …, 2023 - Springer
Acinetobacter baumannii is one of the major pathogenic ESKAPE bacterium, which is
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
responsible for about more than 722,000 cases in a year, globally. Despite the alarming …
Designing a Next-Generation Multiepitope-Based Vaccine against Staphylococcus aureus Using Reverse Vaccinology Approaches
Staphylococcus aureus is a human bacterial pathogen that can cause a wide range of
symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S …
symptoms. As virulent and multi-drug-resistant strains of S. aureus have evolved, invasive S …
An integrative reverse vaccinology, immunoinformatic, docking and simulation approaches towards designing of multi-epitopes based vaccine against monkeypox …
A Ullah, FA Shahid, MU Haq… - Journal of …, 2023 - Taylor & Francis
Monkeypox is a viral zoonotic disease that is caused by the monkeypox virus (MPXV) and is
mainly transmitted to human through close contact with an infected person, animal, or …
mainly transmitted to human through close contact with an infected person, animal, or …
Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa
X Wang, C Liu, N Rcheulishvili, D Papukashvili, F Xie… - npj Vaccines, 2023 - nature.com
Pseudomonas aeruginosa (PA) is a leading cause of hospital-acquired and ventilator-
associated pneumonia. The multidrug-resistance (MDR) rate of PA is increasing making the …
associated pneumonia. The multidrug-resistance (MDR) rate of PA is increasing making the …
Designing multi-epitope-based vaccine targeting surface immunogenic protein of Streptococcus agalactiae using immunoinformatics to control mastitis in dairy cattle
Background Milk provides energy as well as the basic nutrients required by the body. In
particular, milk is beneficial for bone growth and development in children. Based on …
particular, milk is beneficial for bone growth and development in children. Based on …
[HTML][HTML] Biofilm modifiers: The disparity in paradigm of oral biofilm ecosystem
A biofilm is a population of sessile microorganisms that has a distinct organized structure
and characteristics like channels and projections. Good oral hygiene and reduction in the …
and characteristics like channels and projections. Good oral hygiene and reduction in the …