Regulation of sex differences in risk-based decision making by gonadal hormones: insights from rodent models

CA Orsini, LM Truckenbrod, AR Wheeler - Behavioural processes, 2022 - Elsevier
Men and women differ in their ability to evaluate options that vary in their rewards and the
risks that are associated with these outcomes. Most studies have shown that women are …

Sex differences and brain development during puberty and adolescence

JS Peper, SM Burke, LM Wierenga - Handbook of clinical neurology, 2020 - Elsevier
Sex differences in behavior, and whether these behavioral differences are related to sex
differences in brain development, has been a longstanding topic of debate. Presumably, sex …

Balancing risk-return decisions by manipulating the mesofrontal circuits in primates

R Sasaki, Y Ohta, H Onoe, R Yamaguchi, T Miyamoto… - Science, 2024 - science.org
Decision-making is always coupled with some level of risk, with more pathological forms of
risk-taking decisions manifesting as gambling disorders. In macaque monkeys trained in a …

The ghrelin antagonist [D-LYS3]-GHRP-6 decreases signs of risk behavior in a model of gambling addiction in rats by altering dopamine and serotonin metabolism

AA Lebedev, IV Karpova, ER Bychkov… - Neuroscience and …, 2022 - Springer
The effects of the ghrelin receptor antagonist [D-Lys3]-GHRP-6 on elements of gambling
behavior and monoamine metabolism in the brain in rats were studied. A feeding reflex was …

Anabolic-androgenic steroid abuse and cognitive impairment: testosterone IMPAIRS biconditional task performance in male rats

RI Wood, RO Serpa - Behavioural brain research, 2020 - Elsevier
Our goal is to understand the consequences of anabolic-androgenic steroid (AAS) abuse on
cognitive function, using rats as a model. There is relatively little research on how AAS …

Hormonal responses in gambling versus alcohol abuse: a review of human studies

Y Li, N Ramoz, E Derrington, JC Dreher - Progress in Neuro …, 2020 - Elsevier
The endocrine system plays an essential role in communication between various organs of
the body to maintain homeostasis. Both substance use disorders (SUDs) and non-substance …

Chronic high-dose testosterone impairs economic decision making, but has no effect on memory in male rats

RI Wood, MY Chen, E Snow - Behavioural Processes, 2024 - Elsevier
The goal is to understand consequences of anabolic-androgenic steroid (AAS) abuse on
cognitive function, using rats as a model. Economic decision making was evaluated in an …

[HTML][HTML] The decanoate esters of nandrolone, testosterone, and trenbolone induce steroid specific memory impairment and somatic effects in the male rat

S Zelleroth, F Stam, E Nylander, E Kjellgren… - Hormones and …, 2024 - Elsevier
Long-term use of anabolic androgenic steroids (AAS) in supratherapeutic doses is
associated with severe adverse effects, including physical, mental, and behavioral …

Cooperative responses in rats playing a 2× 2 game: Effects of opponent strategy, payoff, and oxytocin

A Donovan, E Ryan, RI Wood - Psychoneuroendocrinology, 2020 - Elsevier
The present study tested cooperation in rats playing a 2× 2 game (2 players, 2 responses) in
an operant chamber, where players choose to cooperate or defect without knowledge of …

Risks of serious injury with testosterone treatment

CJ Yarnell, D Thiruchelvam, DA Redelmeier - The American Journal of …, 2021 - Elsevier
Background Injury causes significant morbidity and mortality that is sometimes attributed to
testosterone and violence. We hypothesized that prescribed testosterone might be …