Amyotrophic lateral sclerosis (ALS) is a disease that progressively annihilates spinal cord
motor neurons, causing severe motor decline and death. The disease is divided into familial …

We show for the first time that a newly developed polyclonal antibody (pAb) can specifically
target the cyanotoxin β-methylamino-L-alanine (BMAA) and can be used to enable direct …

The most severe motor neuron degenerative illness is Amyotrophic Lateral Sclerosis (ALS,
Lou Gehrig's disorder). The aims of the current study are 1) a comparison of genetic and …

Amyotrophic Lateral Sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder that
affects the upper and/or lower motor neurons and is associated with the degeneration of …

Background and purpose The objectives of this study were to define the metabolomic profile
of cerebrospinal fluid in amyotrophic lateral sclerosis (ALS) patients, to model outcome …

Riluzole is the only drug shown to slow the course of amyotrophic lateral sclerosis (ALS).
Patients with ALS-associated dysphagia may have to discontinue riluzole therapy because …

Introduction: Amyotrophic lateral sclerosis (ALS) is an idiopathic neurodegenerative disease
usually fatal in less than three years. Even if standard guidelines are available to diagnose …

Introduction: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease
characterized by motor neuron degeneration in the brain and spinal cord. Treatment …

Mammalian DNA methylation, which exists mainly as 5-methylcytosine within CpG
dinucleotides, is involved in the control of gene expression and is known to be important for …

Increased intracellular calcium (Ca), which might be the consequence of an excess influx
through Ca-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) …