Hypoxic signaling and cholesterol lipotoxicity in fatty liver disease progression

O Tirosh - Oxidative medicine and cellular longevity, 2018 - Wiley Online Library
Cholesterol is the only lipid whose absorption in the gastrointestinal tract is limited by gate‐
keeping transporters and efflux mechanisms, preventing its rapid absorption and …

[PDF][PDF] Non-alcoholic fatty liver disease in non-obese individuals: prevalence, pathogenesis and treatment

E Molina-Molina, M Krawczyk… - Clin. Res. Hepatol …, 2019 - projectfoiegras.eu
Non-alcoholic fatty liver disease (NAFLD) parallels comorbidities such as metabolic
syndrome, dyslipidaemia or diabetes. Although NAFLD is very prevalent in overweight …

A Nomogram Model Based on Noninvasive Bioindicators to Predict 3‐Year Risk of Nonalcoholic Fatty Liver in Nonobese Mainland Chinese: A Prospective Cohort …

X Cai, X Aierken, A Ahmat, Y Cao… - BioMed Research …, 2020 - Wiley Online Library
The purpose of this study is to establish and validate an accurate and personalized
nonalcoholic fatty liver disease (NAFLD) prediction model based on the nonobese …

Decrease in waist-to-hip ratio reduced the development of chronic kidney disease in non-obese non-alcoholic fatty liver disease

YE Chon, HJ Kim, YB Choi, SG Hwang, KS Rim… - Scientific reports, 2020 - nature.com
To date, there are few studies that have evaluated the prognostic impact of changes in
abdominal obesity or weight on long-term adverse kidney outcomes in non-alcoholic fatty …

Real-world comorbidities and treatment patterns among patients with non-alcoholic fatty liver disease receiving phosphatidylcholine as adjunctive therapy in Russia

IV Maev, AA Samsonov, LK Palgova… - BMJ Open …, 2019 - bmjopengastro.bmj.com
Objective Previous research conducted in Russia showed that the number of patients with
non-alcoholic fatty liver disease (NAFLD) and associated metabolic comorbidities is large …

Rescue of Hepatic Phospholipid Remodeling Defect in iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver

W Chamulitrat, C Jansakun, H Li, G Liebisch - Biomolecules, 2020 - mdpi.com
Polymorphisms of group VIA calcium-independent phospholipase A2 (iPLA2β or PLA2G6)
are positively associated with adiposity, blood lipids, and Type-2 diabetes. The ubiquitously …

[HTML][HTML] Association between high fatty liver index and development of colorectal cancer: a nationwide cohort study with 21,592,374 Korean

YJ Choi, DH Lee, KD Han - The Korean Journal of Internal …, 2020 - ncbi.nlm.nih.gov
Methods Data from the National Health Insurance Corporation 2009 to 2012 were analyzed.
NAFLD disease was defined as a fatty liver index> 60 in the absence of alcohol …

Identification of isotschimgine as a novel farnesoid X receptor agonist with potency for the treatment of obesity in mice

Y Li, H Chen, Z Ke, J Huang, L Huang, B Yang… - Biochemical and …, 2020 - Elsevier
Obesity and its associated non-alcoholic fatty liver disease (NAFLD) have become epidemic
medical problems worldwide; however, the current available therapeutic options are limited …

Is it possible to treat nonalcoholic liver disease using a flavanol-based nutraceutical approach? Basic and clinical data

I Hidalgo, M Ortiz-Flores, F Villarreal… - Journal of Basic and …, 2022 - degruyter.com
Nonalcoholic fatty liver disease (NAFLD) is characterized by a spectrum of diseases,
ranging from simple steatosis to hepatocellular carcinoma. The main factors for NAFLD are …

Predictive markers of nonalcoholic fatty liver disease in lean patients. A multinomial regression model and a 2k factorial analysis

E Purón-González, A González-Cantú… - European journal of …, 2021 - journals.lww.com
Objective Nonalcoholic fatty liver disease (NAFLD) is associated with obesity and insulin
resistance; however, there is a group of non-obese patients with NAFLD that need to be …