Transthyretin (TTR) amyloidosis (ATTR amyloidosis) is a multisystemic, multigenotypic
disease resulting from deposition of insoluble ATTR amyloid fibrils in various organs and …

Introduction The most prevalent biological macromolecules in living systems are proteins,
the building block of life, extremely dynamic in structure and functions. Due to several …

Amyloid light-chain (AL) amyloidosis is a rare disease caused by extracellular deposition of
misfolded immunoglobulin light chains. This study aimed to provide an up-to-date estimate …

Abstract CAN2007 was a phase 1/2 study of once-and twice-weekly single-agent
bortezomib in relapsed primary systemic amyloid light chain amyloidosis (AL) amyloidosis …

Amyloidoses are a group of disorders in which soluble proteins aggregate and deposit
extracellularly in tissues as insoluble fibrils, causing organ dysfunction. Clinical …

Cardiac amyloidosis is characterized by clinically significant extracellular amyloid infiltration
of the heart that is usually, but not always, associated with the involvement of other organs …

Immunoglobulin light-chain amyloidosis is a protein aggregation disease that leads to
proteinaceous deposits in a variety of organs in the body and, if untreated, ultimately results …

The objective of the present work was to evaluate the potential of deep learning tools for
characterizing the presence of cardiac amyloidosis from early acquired PET images, ie 15 …

Background: There are limited data concerning the incidence density (ID) of ATTRwt, AL and
AA amyloidosis in the Argentinean population. Our aim was to estimate the ID of ATTRwt, AL …

Light chain (AL) amyloidosis is a form of systemic amyloidosis, causing organ dysfunction,
mainly affecting the heart and kidney. Patient-tailored and risk-adapted decision making is …