Neoantigens: promising targets for cancer therapy

N Xie, G Shen, W Gao, Z Huang, C Huang… - Signal transduction and …, 2023 - nature.com
Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …

Understanding cervical cancer at single-cell resolution

S Yue, Q Wang, J Zhang, Q Hu, C Liu - Cancer Letters, 2023 - Elsevier
Cervical cancer is now the fourth most prevalent malignancy in women worldwide,
representing a tremendous burden of cancer. The heterogeneity of complex tumor …

Development of therapeutic vaccines for the treatment of diseases

Y Tian, D Hu, Y Li, L Yang - Molecular Biomedicine, 2022 - Springer
Vaccines are one of the most effective medical interventions to combat newly emerging and
re-emerging diseases. Prophylactic vaccines against rabies, measles, etc., have excellent …

Human papillomavirus epidemiology and prevention: is there still a gender gap?

G Milano, G Guarducci, N Nante, E Montomoli, I Manini - Vaccines, 2023 - mdpi.com
Background and aim: Human papillomavirus (HPV) is sexually transmitted, one of the three
most common sexually transmitted infections (STIs) in both males and females, and the most …

A novel anti-cancer therapy: CRISPR/Cas9 gene editing

XZ Chen, R Guo, C Zhao, J Xu, H Song, H Yu… - Frontiers in …, 2022 - frontiersin.org
Cancer becomes one of the main causes of human deaths in the world due to the high
incidence and mortality rate and produces serious economic burdens. With more and more …

Advances in autophagy modulation of natural products in cervical cancer

T Tao, P Zhang, Z Zeng, M Wang - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Natural products play a critical role in drug development
and is emerging as a potential source of biologically active metabolites for therapeutic …

Application of cell penetrating peptides as a promising drug carrier to combat viral infections

N Khairkhah, A Namvar, A Bolhassani - Molecular Biotechnology, 2023 - Springer
Novel effective drugs or therapeutic vaccines have been already developed to eradicate
viral infections. Some non-viral carriers have been used for effective drug delivery to a target …

Enhancing the effect of nucleic acid vaccines in the treatment of HPV-related cancers: an overview of delivery systems

IA de Moura, AJD Silva, LS de Macêdo, MCV Invenção… - Pathogens, 2022 - mdpi.com
Prophylactic vaccines against human papillomavirus (HPV) have proven efficacy in those
who have not been infected by the virus. However, they do not benefit patients with …

Human papillomavirus 16 E6/E7 contributes to immune escape and progression of cervical cancer by regulating miR-142–5p/PD-L1 axis

J Ling, Q Sun, Q Tian, H Shi, H Yang, J Ren - Archives of Biochemistry and …, 2022 - Elsevier
Persistent infection of human papillomavirus (HPV) and immune escape are the main
causes of cervical cancer. E6/E7 encoded by HPV16 may be closely related to …

HPV co‐infections with other pathogens in cancer development: A comprehensive review

E Akbari, A Milani, M Seyedinkhorasani… - Journal of Medical …, 2023 - Wiley Online Library
High‐risk human papillomaviruses (HR‐HPVs) cause various malignancies in the
anogenital and oropharyngeal regions. About 70% of cervical and oropharyngeal cancers …